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Inositol polyphosphate-4-phosphatase type I A
go.drugbank.com/bio_entities/BE0018619EnzymeHumansCatalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 3,4-bisphosphate (PtdIns(3,4)P2) (PubMed:15716355, PubMed:20463662). Also catalyzes inositol 1,3,4-trisphosphate and inositol 1,4-bisphosphate (By similarity). ...
Polypeptides: Inositol polyphosphate-4-phosphatase type I AZoledronic acid
go.drugbank.com/drugs/DB00399ApprovedInvestigationalZoledronic acid, or CGP 42'446,[A203120] is a third generation, nitrogen containing bisphosphonate similar to [ibandronic acid], [minodronic acid], and [risedronic acid]. … [L13712,L13715,L13721] Zoledronic acid was first described in the literature in 1994.[A203120] Zoledronic acid was granted FDA approval on 20 August 2001.[L13712]
Synonyms: (1-hydroxy-2-(1H-imidazol-1-yl)ethylidene)bisphosphonic acid, (1-hydroxy-2-imidazol-1-ylethylidene)diphosphonic acidSalts: Zoledronate D,L-Lysine MonohydrateCefalotin
go.drugbank.com/drugs/DB00456ApprovedVet approvedWithdrawnCefalotin is a cephalosporin antibiotic.
Synonyms: 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid, 7-(Thiophene-2-acetamido)cephalosporinCategories: Heterocyclic Compounds, 2-RingLevamisole
go.drugbank.com/drugs/DB00848ApprovedInvestigationalVet approvedWithdrawn[A178123] Interestingly, levamisole has been found as an adulterant in cocaine and can lead to a variety of adverse effects in individuals using this drug.[A178120] … [A178117] It was manufactured by _Janssen_ and first used in 1969 as an agent to treat worm infestations[A178123] Levamisole was approved by the FDA in 1990 as an adjuvant treatment for colon cancer.
Categories: Heterocyclic Compounds, 1-RingProducts: OBAT CACING NO.17 KAM CEK SAN, PVP- LEVAMISOLE POUR-ON SOLUTION 20 %w/vVascular endothelial growth factor A, long form
go.drugbank.com/bio_entities/BE0000163TargetHumansParticipates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A (PubMed:35455969). Involved in protecting cells from hypoxia-mediated cell death (By similarity)
Polypeptides: Vascular endothelial growth factor A, long form3-hydroxy-3-methylglutaryl-coenzyme A reductase
go.drugbank.com/bio_entities/BE0001856TargetPseudomonas mevaloniiP.mevalonii can use mevalonate as sole carbon source. With this enzyme mevalonate is deacetylated to HMG-CoA.
Polypeptides: 3-hydroxy-3-methylglutaryl-coenzyme A reductaseATP synthase F(0) complex subunit a
go.drugbank.com/bio_entities/BE0009014TargetHumansThese two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk (PubMed:37244256). … ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256).
Polypeptides: ATP synthase F(0) complex subunit aSynonyms: Proton-conducting channel, ATP synthase F(0) complex subunit aV-type proton ATPase catalytic subunit A
go.drugbank.com/bio_entities/BE0009200TargetPlasmodium falciparum (isolate 3D7)Catalytic subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates
Polypeptides: V-type proton ATPase catalytic subunit ASynonyms: V-ATPase subunit APreviously treated with a BRAF inhibitor
go.drugbank.com/conditions/DBCOND0164673Drugs: LifileucelSynonyms: Previously treated with a BRAF inhibitorPerioperative Bleeding caused by Hemophilia A
go.drugbank.com/conditions/DBCOND0089513Synonyms: Perioperative Bleeding caused by Hemophilia A