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MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)
smpdb.ca/view/SMP0125720DiseaseMyoneurogastrointestinal encephalopathy, or mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE), is a multisystem disorder caused by mutations in the gene encoding thymidine phosphorylase, which normally uses thymidine an...
Ethylmalonic Encephalopathy
smpdb.ca/view/SMP0125736DiseaseTreatment includes riboflavin and L-carnitine.
Drugs: Adenosine phosphate · NADH · ATP · Levocarnitine · Magnesium cation · Flavin adenine dinucleotide +2 moreDutasteride Action Pathway
smpdb.ca/view/SMP0126518Drug actionDutasteride is a synthetic 4-azasteroid that is used as an antiandrogenic drug. It is used to treat symptomatic benign and symptomatic prostatic hyperplasia (BPH) in adult males. Dutasteride is a dual 5-alpha-reductase inhibitor: it bloc...
Cinnarizine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174985Drug actionCinnarizine is an anti-histaminic drug. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, al...
Carbinoxamine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174988Drug actionCarbinoxamine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, alle...
Tripelennamine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0174989Drug actionTripelennamine is a first-generation ethanolamine H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions s...
Methapyrilene H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175000Drug actionMethapyrilene is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, alle...
Mepyramine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175002Drug actionMepyramine is an antihistamine agent used for the symptomatic treatment of allergy, hypersensitivity reactions, and pruritic skin disorders. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are admi...
Acrivastine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175007Drug actionAcrivastine is an antihistamine agent used for the symptomatic relief of seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, and nasal congestion. H1-antihistamines interfere with the agonist action of histami...
Dexchlorpheniramine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175010Drug actionClemastine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, allergi...