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Benzphetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126989Drug actionBenzphetamine, commonly known as Didrex, is a sympathomimetic used to treat exogenous obesity. It has properties similar to dextroamphetamine. This drug can be used as a short-term treatment of obesity when combined with altered lifestyl...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Vanoxerine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126997Drug actionVanoxerine is an investigational drug that is a selective dopamine transporter antagonist that has not been approved for therapeutic use but is indicated to help treat cocaine addiction. It was developed as a treatment for depression but...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Methylphenidate Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0125204Drug actionMethylphenidate, known commonly as Ritalin, is a central nervous system stimulant used mainly for ADHD, but also for narcolepsy. ADHD is caused by an abnormality in the dopamine transporter gene (DAT1), the D4 receptor gene (DRD-4), and/...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Bupropion Action Pathway
smpdb.ca/view/SMP0125268Drug actionBupropion, known as the brand name Wellbutrin, is a norepinephrine/dopamine reuptake inhibitor (NDRI) used most commonly as a treatment for major depressive disorder (MDD), and seasonal affective disorder (SAD). It can also be used as a ...
Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortMazindol Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126988Drug actionMazindol, commonly known as Sanorex, is a sympathomimetic used to treat Duchenne muscular dystrophy. It has similar side effects to amphetamine but is less toxic. This drug can be used as a short-term treatment of obesity when combined w...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Lisdexamfetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126990Drug actionLisdexamfetamine, known commonly as Vyvanse, is a prodrug of amphetamine paired with lysine and used mainly for treating ADHD and binge eating disorders. The drug was engineered to be abuse-resistant with a delayed release. ADHD is cause...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Dextroamphetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126994Drug actionDextroamphetamine, known commonly as Adderall, is a drug related to amphetamine and is used mainly for treating ADHD and narcolepsy. The drug was approved by the FDA in 2001 for treating ADHD, but the exact mechanisms for its effects are...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Serdexmethylphenidate Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0127003Drug actionSerdexmethylphenidate, known commonly combined with dexmethylphenidate as Azstarys, is a prodrug of dexmethylphenidate (CNS stimulant) used for first-line treatment of ADHD. ADHD is caused by an abnormality in the dopamine transporter ge...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Dexmethylphenidate Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0127004Drug actionDexmethylphenidate, known commonly combined with Serdexmethylphenidate as Azstarys, is a form of methylphenidate (CNS stimulant) used for first-line treatment of ADHD. ADHD is caused by an abnormality in the dopamine transporter gene (DA...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Sibutramine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0127006Drug actionSibutramine, commonly known as Meridia or Reductil, is a norepinephrine, serotonin and dopamine reuptake inhibitor used for the treatment of obesity. This drug was withdrawn from US and Canadian markets for increased risk of heart attack...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1