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T-cell surface glycoprotein CD3 gamma chain
go.drugbank.com/bio_entities/BE0003457TargetHumansIndeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G … When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z.
Synonyms: T-cell receptor T3 gamma chainP2Y purinoceptor 4
go.drugbank.com/bio_entities/BE0009822TargetHumansReceptor for UTP and UDP coupled to G proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP
Synonyms: Uridine nucleotide receptorFunction: G protein-coupled purinergic nucleotide receptor activitySolute carrier family 52, riboflavin transporter, member 2
go.drugbank.com/bio_entities/BE0004841TargetTransporterHumansMay also act as a receptor for 4-hydroxybutyrate (Probable)
Synonyms: PERV-A receptor 1, Porcine endogenous retrovirus A receptor 1Function: 4-hydroxybutyrate receptor activityP2Y purinoceptor 12
go.drugbank.com/bio_entities/BE0000110TargetHumansReceptor for ADP and ATP coupled to G proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Required for normal platelet aggregation and blood coagulation
Synonyms: ADP-glucose receptor, P2Y12 platelet ADP receptorFunction: G protein-coupled adenosine receptor activityGrowth arrest-specific protein 6
go.drugbank.com/bio_entities/BE0010201TargetHumansLigand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell su...
Synonyms: AXL receptor tyrosine kinase ligandT-cell surface glycoprotein CD3
go.drugbank.com/bio_entities/BE0010202TargetHumansIn addition to its role as a TCR coreceptor, it serves as a receptor for ITPRIPL1 (PubMed:38614099). … Indeed, constitutive TCR cycling is dependent on the di-leucine-based (diL) receptor-sorting motif present in CD3G
Synonyms: T-cell receptor T3 delta chain, T-cell receptor T3 zeta chainBeta-galactosidase
go.drugbank.com/bio_entities/BE0009999TargetEnzymeHumansCleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans
Synonyms: Elastin receptor 1C-type lectin domain family 14 member A
go.drugbank.com/bio_entities/BE0005467TargetHumansSynonyms: Epidermal growth factor receptor 5Vitamin B12 transporter BtuB
go.drugbank.com/bio_entities/BE0001470TargetTransporterEscherichia coli (strain K12)Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space (PubMed:4579869). It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.
Synonyms: Cobalamin receptorNeuropilin-1
go.drugbank.com/bio_entities/BE0002129TargetHumansCell-surface receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system.
Synonyms: Vascular endothelial cell growth factor 165 receptor