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C-C chemokine receptor type 9
go.drugbank.com/bio_entities/BE0002463TargetHumansReceptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level
Polypeptides: C-C chemokine receptor type 9Synonyms: G protein-coupled receptor 28Baculoviral IAP repeat-containing protein 5
go.drugbank.com/bio_entities/BE0003408TargetHumansMultitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis (PubMed:20627126, PubMed:21364656, PubMed:25778398, PubMed:28218735, PubMed:9859993). Component of a chromosome passage protein complex (CP...
Polypeptides: Baculoviral IAP repeat-containing protein 5Neuronal acetylcholine receptor subunit alpha-3
go.drugbank.com/bio_entities/BE0003585TargetHumansCHRNA3:CHRNB4 being predominant in neurons of the autonomic ganglia, it is known as ganglionic nicotinic receptor (PubMed:31488329).
Polypeptides: Neuronal acetylcholine receptor subunit alpha-3Gamma-aminobutyric acid receptor subunit theta
go.drugbank.com/bio_entities/BE0003597TargetHumansTheta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:10449790, PubMed:16412217). GABA-gated chloride channels, also named GA...
Polypeptides: Gamma-aminobutyric acid receptor subunit thetaSynonyms: GABA(A) receptor subunit thetaGamma-aminobutyric acid receptor subunit delta
go.drugbank.com/bio_entities/BE0003599TargetHumansDelta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:35355020). GABA-gated chloride channels, also named GABA(A) receptors (...
Polypeptides: Gamma-aminobutyric acid receptor subunit deltaSynonyms: GABA(A) receptor subunit deltaBDNF/NT-3 growth factors receptor
go.drugbank.com/bio_entities/BE0003605TargetHumansReceptor for BDNF/brain-derived neurotrophic factor and NTF4/neurotrophin-4. … Alternatively can also bind NTF3/neurotrophin-3 which is less efficient in activating the receptor but regulates neuron survival through NTRK2 (PubMed:15494731, PubMed:7574684).
Polypeptides: BDNF/NT-3 growth factors receptorSynonyms: Neurotrophic tyrosine kinase receptor type 2Receptor-type tyrosine-protein phosphatase beta
go.drugbank.com/bio_entities/BE0003769TargetHumansPlays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadhe...
Polypeptides: Receptor-type tyrosine-protein phosphatase betaT cell receptor beta constant 1
go.drugbank.com/bio_entities/BE0003779TargetHumansConstant region of T cell receptor (TR) beta chain (PubMed:24600447).
Polypeptides: T cell receptor beta constant 1Cation-dependent mannose-6-phosphate receptor
go.drugbank.com/bio_entities/BE0004494TargetTransporterHumansLysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal
Polypeptides: Cation-dependent mannose-6-phosphate receptorSynonyms: CD Man-6-P receptor, 46 kDa mannose 6-phosphate receptorReceptor tyrosine-protein kinase erbB-4
go.drugbank.com/bio_entities/BE0004772TargetHumansActs as cell-surface receptor for the neuregulins NRG1, NRG2, NRG3 and NRG4 and the EGF family members BTC, EREG and HBEGF. … Ligand binding triggers receptor dimerization and autophosphorylation at specific tyrosine residues that then serve as binding sites for scaffold proteins and effectors.
Polypeptides: Receptor tyrosine-protein kinase erbB-4Synonyms: Tyrosine kinase-type cell surface receptor HER4