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Carbon dioxide
go.drugbank.com/drugs/DB09157ApprovedInvestigationalVet approvedMedical Carbon Dioxide is a liquefied medicinal gas, supplied in cylinders filled to a high pressure. Medical Carbon Dioxide may be used in different situations, e.g. … Carbon dioxide is a colorless, odorless gas vital to life on Earth. This naturally occurring chemical compound is composed of a carbon atom covalently double bonded to two oxygen atoms.
Potassium gluconate
go.drugbank.com/drugs/DB13620ApprovedPotassium gluconate is a salt of [DB01345] and is classified as a food additive by the FDA [L2654]. It is also used as a potassium supplement [L2657]. Potassium is an essential nutrient. … It is the most abundant cation in the intracellular fluid, where it plays a key role in maintaining cell function [A32222].
Succinylcholine
go.drugbank.com/drugs/DB00202ApprovedInvestigational[A19054] It has been widely used for over 50 years,[A299] most commonly in its chloride salt form, as a means of neuromuscular blockade during intubation and surgical procedures. … Succinylcholine is a depolarizing skeletal muscle relaxant consisting of two molecules of the endogenous neurotransmitter [acetylcholine] (ACh) linked by their acetyl groups.
Diphenoxylate
go.drugbank.com/drugs/DB01081ApprovedIllicitInvestigationalA meperidine congener used as an antidiarrheal, usually in combination with atropine. At high doses, it acts like morphine. … When diphenoxylate is used alone, it is classified as a Schedule II.
Mixtures: PHARMANIAGA DIPHENOXYLATE A TABLETArticaine
go.drugbank.com/drugs/DB09009ApprovedInvestigationalArticaine is a dental local anesthetic. Articaine is widely used around the world and is the most popular local anesthetic in many European countries.
Mixtures: SEPTANEST® ADRENALINEE AU 1/100.000, ARTHEEK(R) ARTICAINA AL 4% CON EPINEFRINA 1:100.000Rilzabrutinib
go.drugbank.com/drugs/DB17709ApprovedInvestigational[L53743] ITP is an autoimmune disorder characterized by low platelet count. … Rilzabrutinib is an oral, reversible, covalent inhibitor of Bruton's tyrosine kinase [A259078, L53738] that was approved by the FDA on August 29, 2025, for the treatment of persistent and chronic immune
Prasterone
go.drugbank.com/drugs/DB01708ApprovedInvestigationalNutraceuticalIn Canada, a prescription is required to buy DHEA. … Prasterone, also known as dehydroepiandrosterone (DHEA) is a major C19 steroid produced by the adrenal cortex. It is also produced in small quantities in the testis and the ovary.
Clemastine
go.drugbank.com/drugs/DB00283ApprovedInvestigationalAn ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
Remdesivir
go.drugbank.com/drugs/DB14761ApprovedInvestigational[A222398] Remdesivir (GS-5734) is an adenosine triphosphate analogue first described in the literature in 2016 as a potential treatment for Ebola. … Like other RNA viruses, SARS-CoV-2 depends on an RNA-dependent RNA polymerase (RdRp) enzyme complex for genomic replication, which can be inhibited by a class of drugs known as nucleoside analogues.
Mafenide
go.drugbank.com/drugs/DB06795ApprovedVet approvedWithdrawnMafenide is a sulfonamide-type antimicrobial agent used to treat severe burns. It acts by reducing the bacterial population present in the burn tissue and promotes healing of deep burns. … In November 2022, the use of mafenide acetate (powder for 5% topical solution) was withdrawn by the FDA due to an unresolved confirmatory study required to fulfill the accelerated approval requirements