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Mianserin H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174951Drug actionMianserin is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, allergic...
Esmirtazapine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174952Drug actionEsmirtazapine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, alle...
Trazodone H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174959Drug actionTrazodone is a drug that sometimes acts as a H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such a...
Clofedanol H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174961Drug actionChlophedianol is an H1-antihistamine cough suppressant. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as aller...
Chlorprothixene H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174962Drug actionChlorprothixene is a typical antipsychotic drug of the thioxanthene (tricyclic) class. Chlorprothixene exerts strong blocking effects by blocking the 5-HT2 D1, D2, D3, histamine H1, muscarinic and alpha1 adrenergic receptors. H1-antihist...
Cariprazine H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174972Drug actionCariprazine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, allerg...
Benzquinamide H1 Antihistamine Smooth Muscle Relaxation Action Pathway
smpdb.ca/view/SMP0174975Drug actionBenzquinamide is a discontinued antiemetic compound with antihistaminic, mild anticholinergic, and sedative properties. The mechanism of action is not known, but presumably benzquinamide works via antagonism of muscarinic acetycholine re...
Sphingolipid Signaling
smpdb.ca/view/SMP0538962SignalingIn eukaryotic cells, sphingolipid metabolism begins in the endoplasmic reticulum (ER) with serine palmitoyltransferase (SPT) catalyzing the condensation of serine and palmitoyl‑CoA to generate 3‑ketodihydrosphingosine, which is rapidly r...
Uric Acid Stones
go.drugbank.com/conditions/DBCOND0078710Sorafenib Action Pathway
smpdb.ca/view/SMP0122742Drug actionSorafenib, marketed as Nexavar, is a drug for the treatment of advanced renal cell carcinoma (primary kidney cancer). It is an inhibitor of the RAF kinase protein and cell surface kinases PDGF-beta receptor, VEGF 2 and 3 receptor (many s...