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Displaying results 1201 - 1210 of 1993 in total
  1. Target

    Tumor necrosis factor receptor superfamily member 5

    go.drugbank.com/bio_entities/BE0001196
    TargetHumans

    Receptor for TNFSF5/CD40LG (PubMed:31331973).

    Polypeptides: Tumor necrosis factor receptor superfamily member 5Synonyms: CD40L receptor
  2. Target

    Prolow-density lipoprotein receptor-related protein 1

    go.drugbank.com/bio_entities/BE0002110
    TargetHumans

    Acts as an LRPAP1 alpha-2-macroglobulin receptor (PubMed:1702392, PubMed:26142438). … Also acts as a receptor for IGFBP3 to mediate cell growth inhibition (PubMed:9252371)

    Polypeptides: Prolow-density lipoprotein receptor-related protein 1Synonyms: Apolipoprotein E receptor, Alpha-2-macroglobulin receptor
  3. Target

    Gamma-aminobutyric acid receptor subunit beta-3

    go.drugbank.com/bio_entities/BE0002345
    TargetHumans

    Beta subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:14993607, PubMed:18514161, PubMed:22243422, PubMed:22303015, PubMed:2490...

    Polypeptides: Gamma-aminobutyric acid receptor subunit beta-3Synonyms: GABA(A) receptor subunit beta-3
  4. Target

    Tumor necrosis factor receptor superfamily member 10B

    go.drugbank.com/bio_entities/BE0003433
    TargetHumans

    Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor.

    Polypeptides: Tumor necrosis factor receptor superfamily member 10BSynonyms: Death receptor 5, TRAIL receptor 2
  5. Target

    Tumor necrosis factor receptor superfamily member 9

    go.drugbank.com/bio_entities/BE0003463
    TargetHumans

    Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable)

    Polypeptides: Tumor necrosis factor receptor superfamily member 9Synonyms: 4-1BB ligand receptor
  6. Target

    Gamma-aminobutyric acid receptor subunit gamma-3

    go.drugbank.com/bio_entities/BE0003594
    TargetHumans

    Gamma subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (By similarity). GABA-gated chloride channels, also named GABA(A) receptors (GA...

    Polypeptides: Gamma-aminobutyric acid receptor subunit gamma-3Synonyms: GABA(A) receptor subunit gamma-3
  7. Target

    Acetylcholine receptor subunit alpha-type unc-38

    go.drugbank.com/bio_entities/BE0004925
    TargetCaenorhabditis elegans

    Alpha subunit of nicotinic acetylcholine receptor (nAChR) (PubMed:15990870, PubMed:20027209, PubMed:9221782).

    Polypeptides: Acetylcholine receptor subunit alpha-type unc-38
  8. Target

    Acetylcholine receptor subunit beta-type lev-1

    go.drugbank.com/bio_entities/BE0004927
    TargetCaenorhabditis elegans

    Non-alpha subunit of nicotinic acetylcholine receptor (nAChR). Involved in nAChR sensitivity to nicotine.

    Polypeptides: Acetylcholine receptor subunit beta-type lev-1
  9. Target

    Calcitonin gene-related peptide type 1 receptor

    go.drugbank.com/bio_entities/BE0009009
    TargetHumans

    G protein-coupled receptor which specificity is determined by its interaction with receptor-activity-modifying proteins (RAMPs) (PubMed:32296767, PubMed:33602864, PubMed:8626685). … Together with RAMP1, form the receptor complex for calcitonin-gene-related peptides CALCA/CGRP1 and CALCB/CGRP2 (PubMed:33602864).

    Polypeptides: Calcitonin gene-related peptide type 1 receptorSynonyms: Calcitonin receptor-like receptor, CGRP type 1 receptor
  10. Target

    Receptor-interacting serine/threonine-protein kinase 1

    go.drugbank.com/bio_entities/BE0009531
    TargetHumans

    Serine-threonine kinase which is a key regulator of TNF-mediated apoptosis, necroptosis and inflammatory pathways (PubMed:17703191, PubMed:24144979, PubMed:31827280, PubMed:31827281, PubMed:32657447, PubMed:35831301). Exhibits kinase act...

    Polypeptides: Receptor-interacting serine/threonine-protein kinase 1Synonyms: Receptor-interacting protein 1