Search

Displaying results 1211 - 1220 of 10000 in total
  1. Drug

    Metformin

    go.drugbank.com/drugs/DB00331
    ApprovedInvestigational

    It is commonly described as an "insulin sensitizer", leading to a decrease in insulin resistance and a clinically significant reduction of plasma fasting insulin levels. … Metformin is a biguanide antihyperglycemic agent and first-line pharmacotherapy used in the management of type II diabetes.

    Mixtures: VELMETIA LP, Vildagliptin/Metformin 1A Pharma 50 mg/850 mg – FilmtablettenCategories: MATE 1 Substrates, MATE 2 Substrates
  2. Drug

    Pioglitazone

    go.drugbank.com/drugs/DB01132
    ApprovedInvestigational

    [L11416,L11419,L11422,L11425] It is administered as a racemic mixture, though there is no pharmacologic difference between the enantiomers and they appear to interconvert _in vivo_ with little consequence … Pioglitazone is an antihyperglycemic used as an adjunct to diet, exercise, and other antidiabetic medications to manage type 2 diabetes mellitus.

    Mixtures: PIO-ALA 15/600 MG FILM KAPLI TABLET ,30 ADET, PIO-ALA 15/600 MG FILM KAPLI TABLET ,90 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates
  3. Indication

    Vitamin Deficiencies

    go.drugbank.com/conditions/DBCOND0106956
    Drugs: Ascorbic acid · Biotin · Cholecalciferol · Cobaltous sulfate · Cyanocobalamin · DL-alpha tocopheryl acetate +12 more
    Synonyms: Avitaminosis A B B1 B2 etc.
  4. Drug

    Omeprazole

    go.drugbank.com/drugs/DB00338
    ApprovedInvestigationalVet approved

    Originally approved by the FDA in 1989, omeprazole is a _proton-pump inhibitor_, used to treat gastric acid-related disorders.

    Mixtures: ORAZOLE ® 10 MG CAPSULACategories: P-glycoprotein inhibitors, P-glycoprotein substrates
  5. Drug

    Sunflower oil

    go.drugbank.com/drugs/DB14329
    Investigational

    Sunflower oil is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

    Categories: Complex MixturesProducts: OrgaPlus Super Care Balm for combination and oi ly skin type 20g, OrgaPlus Super Care Balm for combination and oi ly skin type 14g
  6. Drug

    Fluoxetine

    go.drugbank.com/drugs/DB00472
    ApprovedInvestigationalVet approved

    Fluoxetine is a 2nd generation antidepressant categorized as a selective serotonin reuptake inhibitor (SSRI).

    Synonyms: (+-)-N-Methyl-3-phenyl-3-((alpha,alpha,alpha-trifluoro-P-tolyl)oxy)propylamine, (+-)-N-Methyl-gamma-(4-(trifluoromethyl)phenoxy)benzenepropanamineInternational brands: Animex-On
  7. Drug

    Fentanyl

    go.drugbank.com/drugs/DB00813
    ApprovedIllicitInvestigationalVet approved

    Fentanyl, a potent opioid agonist, was developed in the 1950s to fill a need for strong and rapid analgesia. … Fentanyl's high potency has also made it a common adulterant in illicit drugs, especially heroin.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSynonyms: N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide, N-phenyl-N-[1-(2-phenylethyl)-4-piperidinyl]propanamide
  8. Pathway

    Pyruvate Dehydrogenase Complex Deficiency

    smpdb.ca/view/SMP0000212
    Disease

    Pyruvate dehydrogenase complex deficiency results from a mutation in the E1-alpha polypeptide gene (PDHA1). … PDHA1 encodes the pyruvate dehydrogenase complex (PDC) a critical complex that converts pyruvate from glycolysis to acetyl CoA for the citric acid cycle.

    Drugs: Pyruvic acid · Biotin · Adenosine phosphate · Glutathione · NADH · ATP +13 more
    Enzymes: Acyl-coenzyme A thioesterase 12, L-lactate dehydrogenase A-like 6A
  9. Drug

    RGG0853

    go.drugbank.com/drugs/DB18669
    Experimental

    RGG0853 is an E1A lipid complex, a repressor gene complexed with a cationic lipid vector.

    Synonyms: HER-2/neu inhibitor, RGG0853, E1A lipid complex
  10. Drug

    TALL-104

    go.drugbank.com/drugs/DB17360
    Investigational

    Synonyms: Human major histocompatibility complex (MHC) non-restricted T-cell line 104