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ATP-dependent RNA helicase A
go.drugbank.com/bio_entities/BE0014303TargetHumansPlays a role as a transcriptional coactivator acting as a bridging factor between polymerase II holoenzyme and transcription factors or cofactors, such as BRCA1, CREBBP, RELA and SMN1 (PubMed:11038348, … Plays a role in mRNA translation (PubMed:28355180).
Polypeptides: ATP-dependent RNA helicase ASynonyms: RNA helicase AOryctolagus cuniculus skin
go.drugbank.com/drugs/DB10607ApprovedOryctolagus cuniculus skin or pelt is used in allergenic testing.
Synonyms: European rabbit skin extractCaffeine
go.drugbank.com/drugs/DB00201ApprovedInvestigational[T716] Caffeine is also used in a variety of cosmetic products and can be administered topically, orally, by inhalation, or by injection. … Caffeine is a drug of the methylxanthine class used for a variety of purposes, including certain respiratory conditions of the premature newborn, pain relief, and to combat drowsiness.
Mixtures: SAL DE FRUTAS LUA ACTIVE, Saridon - ACategories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingAcetyl-coenzyme A synthetase, cytoplasmic
go.drugbank.com/bio_entities/BE0000350TargetEnzymeHumansCan also utilize propionate with a much lower affinity (PubMed:38369012). Catalyzes the conversion of lactate into lactoyl-CoA (PubMed:39561764). … Acts as a chromatin-bound transcriptional coactivator that up-regulates histone acetylation and expression of neuronal genes (By similarity).
Polypeptides: Acetyl-coenzyme A synthetase, cytoplasmicHydroxyacyl-coenzyme A dehydrogenase, mitochondrial
go.drugbank.com/bio_entities/BE0000377TargetHumansPlays a role in the maintenance of normal spermatogenesis through the reduction of fatty acid accumulation in the testes (By similarity) … Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion
Polypeptides: Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialSynonyms: Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenaseEphrin type-A receptor 2
go.drugbank.com/bio_entities/BE0000841TargetHumansWith ephrin-A2/EFNA2 may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis … May also participate in UV radiation-induced apoptosis and have a ligand-independent stimulatory effect on chemotactic cell migration.
Polypeptides: Ephrin type-A receptor 2Ribose-5-phosphate isomerase A
go.drugbank.com/bio_entities/BE0001557TargetThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
Polypeptides: Ribose-5-phosphate isomerase ASynonyms: Phosphoriboisomerase AInositol-trisphosphate 3-kinase A
go.drugbank.com/bio_entities/BE0001627TargetHumansCatalyzes the phosphorylation of 1D-myo-inositol 1,4,5-trisphosphate (InsP3) into 1D-myo-inositol 1,3,4,5-tetrakisphosphate and participates to the regulation of calcium homeostasis
Polypeptides: Inositol-trisphosphate 3-kinase ASynonyms: IP3K A, IP3 3-kinase AComplement C1q subcomponent subunit A
go.drugbank.com/bio_entities/BE0002094TargetHumansThe C1Q subcomplex is activated by a hexamer of IgG complexed with antigens, while it is activated by a pentameric IgM (PubMed:19706439, PubMed:24626930, PubMed:29449492). … Core component of the complement C1 complex, a multiprotein complex that initiates the classical pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens
Polypeptides: Complement C1q subcomponent subunit AAmine oxidase [flavin-containing] A
go.drugbank.com/bio_entities/BE0002198TargetEnzymeHumansCatalyzes the oxidative deamination of primary and some secondary amine such as neurotransmitters, with concomitant reduction of oxygen to hydrogen peroxide and has important functions in the metabolism
Polypeptides: Amine oxidase [flavin-containing] ASynonyms: MAO-A, Monoamine oxidase type A