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Growth hormone-releasing hormone receptor
go.drugbank.com/bio_entities/BE0000625TargetHumansReceptor for GRF, coupled to G proteins which activate adenylyl cyclase. Stimulates somatotroph cell growth, growth hormone gene transcription and growth hormone secretion
Polypeptides: Growth hormone-releasing hormone receptorSynonyms: GRF receptor, GHRH receptorGlutamate receptor ionotropic, NMDA 3A
go.drugbank.com/bio_entities/BE0000641TargetHumansForms excitatory glycinergic receptor complexes with GluN1 alone which are activated by glycine binding to the GluN1 and GluN3 subunits (PubMed:38598639). … Forms glutamatergic receptor complexes with GluN1 and GluN2 subunits which are activated by glycine binding to the GluN1 and GluN3 subunits and L-glutamate binding to GluN2 subunits (By similarity).
Polypeptides: Glutamate receptor ionotropic, NMDA 3ASynonyms: N-methyl-D-aspartate receptor subtype 3AInterleukin-2 receptor subunit beta
go.drugbank.com/bio_entities/BE0000651TargetHumansReceptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Polypeptides: Interleukin-2 receptor subunit betaSynonyms: IL-2 receptor subunit beta, High affinity IL-2 receptor subunit betaUrokinase plasminogen activator surface receptor
go.drugbank.com/bio_entities/BE0000717TargetHumansGPI-anchored receptor that recruits and activates the urokinase-type plasminogen activator (uPA) at the cell surface.
Polypeptides: Urokinase plasminogen activator surface receptorGranulocyte colony-stimulating factor receptor
go.drugbank.com/bio_entities/BE0000793TargetHumansReceptor for granulocyte colony-stimulating factor (CSF3), essential for granulocytic maturation.
Polypeptides: Granulocyte colony-stimulating factor receptorSynonyms: G-CSF receptorGlutamate receptor ionotropic, kainate 3
go.drugbank.com/bio_entities/BE0000832TargetHumansThe receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:7719709). … Ionotropic glutamate receptor that functions as a cation-permeable ligand-gated ion channel, gated by L-glutamate and the glutamatergic agonist kainic acid.
Polypeptides: Glutamate receptor ionotropic, kainate 3Synonyms: Glutamate receptor 7, Excitatory amino acid receptor 5Glucagon-like peptide 1 receptor
go.drugbank.com/bio_entities/BE0000857TargetHumansG protein-coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449, PubMed:7517895, PubMed:8216285, PubMed:8405712).
Polypeptides: Glucagon-like peptide 1 receptorSynonyms: GLP-1 receptorReceptor activity-modifying protein 3
go.drugbank.com/bio_entities/BE0000861TargetHumansestrogen receptor 1 (GPER1) (PubMed:23674134, PubMed:9620797). … Together with CALCRL, form a receptor complex for adrenomedullin/ADM and intermedin/ADM2 (PubMed:32296767). Together with CALCR, act as a receptor complex for amylin/IAPP (PubMed:35324283)
Polypeptides: Receptor activity-modifying protein 3Synonyms: Calcitonin-receptor-like receptor activity-modifying protein 3TGF-beta receptor type-2
go.drugbank.com/bio_entities/BE0001861TargetHumansTransmembrane serine/threonine kinase forming with the TGF-beta type I serine/threonine kinase receptor, TGFBR1, the non-promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. … Activated TGFBR1 phosphorylates SMAD2 which dissociates from the receptor and interacts with SMAD4.
Polypeptides: TGF-beta receptor type-2Synonyms: TGF-beta receptor type II, TGF-beta type II receptorGlucagon-like peptide 2 receptor
go.drugbank.com/bio_entities/BE0002134TargetHumansThis is a receptor for glucagon-like peptide 2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase
Polypeptides: Glucagon-like peptide 2 receptorSynonyms: GLP-2 receptor