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Agalsidase beta
go.drugbank.com/drugs/DB00103ApprovedInvestigational[A220228,A220233] Use of agalsidase beta has decreased in Europe, in favor of agalsidase alfa, after a contamination event in 2009. … [A220343] Agalsidase beta was granted FDA approval on 24 April 2003.[L16383]
ATP synthase F(1) complex subunit delta, mitochondrial
go.drugbank.com/bio_entities/BE0000484TargetEnzymeHumansATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Subunit delta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated
Polypeptides: ATP synthase F(1) complex subunit delta, mitochondrialDihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
go.drugbank.com/bio_entities/BE0001298TargetAzotobacter vinelandiiThe pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
Polypeptides: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complexSynonyms: Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complexATP synthase F(1) complex subunit alpha, mitochondrial
go.drugbank.com/bio_entities/BE0003840TargetHumansATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Subunit alpha, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated
Polypeptides: ATP synthase F(1) complex subunit alpha, mitochondrialActin-related protein 2/3 complex subunit 1B
go.drugbank.com/bio_entities/BE0004249TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:11741539, PubMed:9230079). … The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:11741539, PubMed:9230079).
Polypeptides: Actin-related protein 2/3 complex subunit 1BSynonyms: Arp2/3 complex 41 kDa subunitActin-related protein 2/3 complex subunit 3
go.drugbank.com/bio_entities/BE0004253TargetHumansComponent of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). … The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079).
Polypeptides: Actin-related protein 2/3 complex subunit 3Synonyms: Arp2/3 complex 21 kDa subunitATP synthase F(0) complex subunit g, mitochondrial
go.drugbank.com/bio_entities/BE0009022TargetHumansPart of the complex F(0) domain (PubMed:37244256) … ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256).
Polypeptides: ATP synthase F(0) complex subunit g, mitochondrialB Vitamin Deficiency
go.drugbank.com/conditions/DBCOND0067035Synonyms: Vitamin B complex deficiency, B-complex deficiency NOSTetracycline
go.drugbank.com/drugs/DB00759ApprovedInvestigationalVet approvedWithdrawnThe FDA withdrew its approval for the use of all liquid oral drug products formulated for pediatric use containing tetracycline in a concentration greater than 25 mg/ml. … It exerts a bacteriostatic effect on bacteria by binding reversible to the bacterial 30S ribosomal subunit and blocking incoming aminoacyl tRNA from binding to the ribosome acceptor site.
Products: PIPERACILLINA E TAZOBACTAM EG, COMTREX JARABETagraxofusp
go.drugbank.com/drugs/DB14731ApprovedInvestigational[A253762] It was also approved by the European Commission on January 7, 2021.[L43712] … a myeloid malignancy in the dendritic cell lineage.