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Displaying results 121 - 124 of 124 in total
  1. Pathway

    Autophagy

    smpdb.ca/view/SMP0578913
    Signaling

    Autophagy is a highly conserved, multistep lysosomal degradation pathway that plays a central role in cellular homeostasis by sequestering cytoplasmic proteins, damaged organelles, and macromolecules into double‑membrane autophagosomes f...

    Drugs: Adenosine phosphate · Calcium
    Enzymes: Gamma-aminobutyric acid receptor-associated protein, Gamma-aminobutyric acid receptor-associated protein-like 2
  2. Pathway

    Ethylmorphine Action Pathway

    smpdb.ca/view/SMP0000681
    Drug action

    Morphine can also bind and inhibit gamma-Aminobutyric acid (GABA) inhibitory interneurons.

    Drugs: ATP · Norepinephrine · Dopamine · Potassium cation · Calcium · Ethylmorphine
    Enzymes: Sodium/potassium-transporting ATPase subunit gamma
  3. Pathway

    Pregabalin Action Pathway

    smpdb.ca/view/SMP0125115
    Drug action

    Although the structure of pregabalin is similar to gamma-aminobutyric acid (GABA), it does not bind to GABA receptors. … Pregabalin is structurally similar to gamma-aminobutyric acid (GABA) - an inhibitory neurotransmitter. Its properties include anxiolytic, anticonvulsant and analgesic effects.

    Drugs: L-Glutamine · Glutamic acid · Pregabalin · Calcium
    Enzymes: Excitatory amino acid transporter 2
  4. Pathway

    Metabolism and Physiological Effects of Beta-Alanine

    smpdb.ca/view/SMP0126732
    Metabolic

    beta-Alanine is the only naturally occurring beta-amino acid - an amino acid in which the amino group is at the beta-position from the carboxylate group. … Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, beta-alanine may act as a false transmitter replacing gamma-aminobutyric acid.

    Drugs: Ademetionine · Zinc · beta-Alanine · 1-Methylhistidine