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Voltage-dependent P/Q-type calcium channel
go.drugbank.com/bio_entities/BE0008717TransporterTargetHumansVoltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone … The isoform alpha-1A gives rise to P and/or Q-type calcium currents.
Polypeptides: Voltage-dependent P/Q-type calcium channel subunit alpha-1ASynonyms: Brain calcium channel I, Voltage-gated calcium channel subunit alpha Cav2.1Calcium/calmodulin-dependent protein kinase type 1G
go.drugbank.com/bio_entities/BE0004147TargetHumansCalcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1 (By similarity)
Polypeptides: Calcium/calmodulin-dependent protein kinase type 1GCalcium-activated potassium channel subunit alpha-1
go.drugbank.com/bio_entities/BE0004784TargetMousePotassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). It is also activated by the concentration of cytosolic Mg(2+). Its activation dampens the excitatory events that el...
Polypeptides: Calcium-activated potassium channel subunit alpha-1Synonyms: Calcium-activated potassium channel, subfamily M subunit alpha-1Calcium/calmodulin-dependent protein kinase kinase 1
go.drugbank.com/bio_entities/BE0009418TargetHumansCalcium/calmodulin-dependent protein kinase that belongs to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Phosphorylates CAMK1, CAMK1D, CAMK1G and CAMK4.
Polypeptides: Calcium/calmodulin-dependent protein kinase kinase 1Synonyms: Calcium/calmodulin-dependent protein kinase kinase alpha85/88 kDa calcium-independent phospholipase A2
go.drugbank.com/bio_entities/BE0001077TargetHumansIn response to glucose, amplifies calcium influx in pancreatic beta cells to promote INS secretion (By similarity) … Calcium-independent phospholipase involved in phospholipid remodeling with implications in cellular membrane homeostasis, mitochondrial integrity and signal transduction.
Polypeptides: 85/88 kDa calcium-independent phospholipase A2Synonyms: Intracellular membrane-associated calcium-independent phospholipase A2 betaCalcium/calmodulin-dependent protein kinase type IV
go.drugbank.com/bio_entities/BE0004042TargetHumansCalcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK4 signaling cascade and regulates, mainly by phosphorylation, the activity of several transcription activators
Polypeptides: Calcium/calmodulin-dependent protein kinase type IVVoltage-dependent calcium channel gamma-2 subunit
go.drugbank.com/bio_entities/BE0005108TargetHumansThought to stabilize the calcium channel in an inactivated (closed) state
Polypeptides: Voltage-dependent calcium channel gamma-2 subunitSynonyms: Neuronal voltage-gated calcium channel gamma-2 subunitCalcium-transporting ATPase type 2C member 1
go.drugbank.com/bio_entities/BE0000218TargetHumansATP-driven pump that supplies the Golgi apparatus with Ca(2+) and Mn(2+) ions, both essential cofactors for processing and trafficking of newly synthesized proteins in the secretory pathway (PubMed:12707275, PubMed:16192278, PubMed:20439...
Polypeptides: Calcium-transporting ATPase type 2C member 1Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1
go.drugbank.com/bio_entities/BE0004522TargetTransporterHumansthus providing calcium for the downstream calcium channel MCU that directly releases it into mitochondria matrix (By similarity). … Inositol 1,4,5-trisphosphate-gated calcium channel that, upon inositol 1,4,5-trisphosphate binding, mediates calcium release from the endoplasmic reticulum (ER) (PubMed:10620513, PubMed:27108797).
Polypeptides: Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1Function: calcium channel inhibitor activityInositol 1,4,5-trisphosphate-gated calcium channel ITPR2
go.drugbank.com/bio_entities/BE0009594TargetHumansInositol 1,4,5-trisphosphate-gated calcium channel that upon inositol 1,4,5-trisphosphate binding transports calcium from the endoplasmic reticulum lumen to cytoplasm.
Polypeptides: Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2Function: calcium ion binding