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Azelastine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175036Drug actionAzelastine is a histamine H1-receptor antagonist used intranasally to treat allergic and vasomotor rhinitis and in an ophthalmic solution to treat allergic conjunctivitis. H1-antihistamines interfere with the agonist action of histamine ...
Chlorpheniramine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175042Drug actionChlorpheniramine is a histamine-H1 receptor antagonist indicated for the management of symptoms associated with upper respiratory allergies. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are admi...
Esmirtazapine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175044Drug actionEsmirtazapine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, alle...
Dimetotiazine H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175045Drug actionDimetotiazine is an H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis, alle...
Dexchlorpheniramine maleate H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175046Drug actionDexchlorpheniramine maleate is a first generation H1-antihistamine used to treat allergic and vasomotor rhinitis, allergic conjunctivitis, and mild urticaria and angioedema. H1-antihistamines interfere with the agonist action of histamin...
Zuclopenthixol H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175061Drug actionZuclopenthixol is a weak H1-antihistamine. H1-antihistamines interfere with the agonist action of histamine at the H1 receptor and are administered to attenuate inflammatory process in order to treat conditions such as allergic rhinitis,...
Aripiprazole lauroxil H1-Antihistamine Blood Vessel Constriction Action Pathway
smpdb.ca/view/SMP0175069Drug actionAripiprazole lauroxil is a long-acting injectable atypical antipsychotic drug used in the treatment of schizophrenia in adult patients. It is a prodrug of aripiprazole, which acts as a partial agonist at the D2 and 5-HT1A receptors, and ...
HIF-1 (Hypoxia) Signaling
smpdb.ca/view/SMP0546631SignalingHypoxia triggers stabilization of hypoxia‑inducible factors (HIFs), oxygen‑sensitive transcription factors that orchestrate adaptive responses by inducing genes involved in angiogenesis, erythropoiesis, metabolism, and survival. Under no...
Pyrazinamide Action Pathway
smpdb.ca/view/SMP0718082Drug actionThe pyrazinamide (PZA) pathway plays a crucial role in the treatment of Mycobacterium tuberculosis infection. Pyrazinamide is a prodrug that requires activation by the bacterial enzyme pyrazinamidase/nicotinamidase (PncA). This enzyme co...
Vitamin B6 Metabolism
smpdb.ca/view/SMP0000017MetabolicAs is commonly known there are many vitamins, the vitamin B complex group being one of the most well known. An important vitamin B complex group vitamin is vitamin B6, which is water-soluble. Moreover, this vitamin comes in various forms...
Drugs: Pyridoxal phosphate · Pyridoxal · Pyridoxine · Magnesium cation · Zinc · Pyridoxamine-5'-Phosphate +3 more