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Displaying results 1331 - 1340 of 10000 in total
  1. Drug

    Debrisoquine

    go.drugbank.com/drugs/DB04840
    Approved

    An adrenergic neuron-blocking drug similar in effects to guanethidine. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme.

  2. Drug

    Technetium Tc-99m succimer

    go.drugbank.com/drugs/DB09436
    Approved

    function in patients with renal parenchymal disorders. … It works by binding to the cortical region of the kidneys. Technetium Tc-99m succimer is used with gamma scintigraphy or single-photon emission computed tomography (SPECT).

    Categories: Compounds used in a research, industrial, or household setting
  3. Target

    Prostacyclin receptor

    go.drugbank.com/bio_entities/BE0000475
    TargetHumans

    Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase

    Polypeptides: Prostacyclin receptorSynonyms: PGI receptor, PGI2 receptor
  4. Target

    Glucagon receptor

    go.drugbank.com/bio_entities/BE0000527
    TargetHumans

    G protein-coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis.

    Polypeptides: Glucagon receptorFunction: glucagon receptor activity
  5. Target

    Erythropoietin receptor

    go.drugbank.com/bio_entities/BE0000654
    TargetHumans

    Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation (PubMed:10388848, PubMed:2163695, PubMed:2163696, PubMed:8662939, PubMed:9774108).

    Polypeptides: Erythropoietin receptorFunction: erythropoietin receptor activity
  6. Target

    Nociceptin receptor

    go.drugbank.com/bio_entities/BE0002378
    TargetHumans

    G protein-coupled opioid receptor that functions as a receptor for the endogenous neuropeptide nociceptin.

    Polypeptides: Nociceptin receptorSynonyms: Orphanin FQ receptor, Kappa-type 3 opioid receptor
  7. Target

    Thrombopoietin receptor

    go.drugbank.com/bio_entities/BE0003440
    TargetHumans

    Receptor for thrombopoietin that regulates hematopoietic stem cell renewal, megakaryocyte differentiation, and platelet formation.

    Polypeptides: Thrombopoietin receptorFunction: thrombopoietin receptor activity
  8. Target

    Poliovirus receptor

    go.drugbank.com/bio_entities/BE0004247
    TargetHumans

    Mediates NK cell adhesion and triggers NK cell effector functions. Binds two different NK cell receptors: CD96 and CD226. These interactions accumulates at the cell-cell contact site, leading to the formation of a mature immunological sy...

    Polypeptides: Poliovirus receptor
  9. Target

    NMDA receptor

    go.drugbank.com/bio_entities/BE0004956
    TargetHumans

    Forms excitatory glycinergic receptor complexes with GluN1 alone which are activated by glycine binding to the GluN1 and GluN3 subunits. … Forms excitatory glycinergic receptor complexes with GluN1 alone which are activated by glycine binding to the GluN1 and GluN3 subunits (PubMed:38598639).

    Polypeptides: Glutamate receptor ionotropic, NMDA 1, Glutamate receptor ionotropic, NMDA 2ASynonyms: Glutamate [NMDA] receptor subunit zeta-1, N-methyl-D-aspartate receptor subunit NR1
  10. Target

    Somatostatin receptor

    go.drugbank.com/bio_entities/BE0010008
    TargetHumans