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Dihydroergocryptine Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126659Drug actionAlpha-dihydroergocryptine is usually referred to the mixture of the alpha and beta dihydroergocryptine. These two compounds are differentiated in the position of a methyl group. This structural difference is due to a proteinogenic amino ...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortChikungunya vaccine (live, attenuated)
go.drugbank.com/drugs/DB18701ApprovedInvestigational[A262051] Prior to 2013, chikungunya virus cases and outbreaks had been identified in countries in Africa, Asia, Europe, and the Indian and Pacific Oceans. … Chikungunya virus (CHIKV) is a member of the Alphavirus genus that was first identified in Tanzania in 1952.[A262051] It is spread primarily by the bite of infected mosquitos of the _Aedes_ genus.
Pozanicline
go.drugbank.com/drugs/DB05458InvestigationalNeuronal nicotinic acetylcholine receptors (nAChRs) modulate the release of several important neurotransmitters, such as acetylcholine and dopamine. … In radioligand binding studies, ABT-089 has shown selectivity toward the alpha4beta2 nAChR subtype as compared to the alpha7 and alpha1beta1deltagamma nAChR subtypes.
Categories: Heterocyclic Compounds, 1-RingTrenibotulinumtoxinE
go.drugbank.com/drugs/DB19082Approved[L64118] It is the first and only rapid-onset, short-duration botulinum neurotoxin serotype E approved in Europe.[L64118] … and resolve within 2 to 3 weeks.
Synonyms: BOTULINUM NEUROTOXIN SEROTYPE E (BONT/E) (EB-001), BONTOXILYSIN-EPolyvinyl alcohol
go.drugbank.com/drugs/DB11060ApprovedPolyvinyl alcohol is found in ophthalmic solutions as a lubricant to prevent irritation or to relieve dryness of the eyes [L2826]. … Polyvinyl alcohol is a water-soluble synthetic polymer obtained by polymerization of vinyl alcohol.
Mixtures: FULLFRESH 5,60 MG/2,40 MG TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİ, NOVAQUA %1,4 + %0,6 TEK DOZLUK GÖZ DAMLASI, ÇÖZELTİ, 30 ADETCategories: Compounds used in a research, industrial, or household settingErgoloid mesylate Mechanism of Action Action Pathway
smpdb.ca/view/SMP0126658Drug actionErgoloid Mesylate is an equiproportional preparation of three different ergotamantriones: dihydroergocornine, dihydroergocristine, and dihydroergocryptine. All these components are produced by the fungus Claviceps purpurea and are all de...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortFluconazole
go.drugbank.com/drugs/DB00196ApprovedInvestigationalIt was initially approved by the FDA in 1990. This drug is an _azole_ antifungal, in the same drug family as [ketoconazole] and [itraconazole]. … Fluconazole has many advantages over the other antifungal drugs including the option of oral administration. The side effect profile of this drug is minimal.
Mixtures: FUNEX® - S TABLETA, BATEN ® S TABLETAS RECUBIERTASCategories: P-glycoprotein inhibitors, Cytochrome P-450 CYP3A InhibitorsMetoprolol
go.drugbank.com/drugs/DB00264ApprovedInvestigationalMetoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. … [T274] To this date, it is one of the preferred beta-blockers in general clinical guidelines and it is widely prescribed in the Netherlands, New Zealand, and the US.
Mixtures: METOPROLOL HCT S 100/12.5, METOPROLOL HCT S 100/12.5Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AntagonistsThiethylperazine Dopamine Antagonist Action Pathway
smpdb.ca/view/SMP0126476Drug actionThiethylperazine' s antipsychotic effect is due to antagonism at dopamine and serotonin type 2 receptors, with greater activity at serotonin 5-HT2 receptors than at dopamine type-2 receptors.
Drugs: Pyridoxal phosphate · Tyrosine · Sapropterin · Thiethylperazine · Dopamine · Levodopa +2 moreEnzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortParathyroid hormone
go.drugbank.com/drugs/DB05829ApprovedInvestigationalPreotact is used in the treatment of osteoporosis in postmenopausal women at high risk of osteoporotic fractures and is marketed in Europe by Nycomed. … Preos is a registered trade mark owned by NPS Pharmaceuticals, Inc. The name Preos and the New Drug Application is pending approval by the U.S. Food and Drug Administration (FDA).
Synonyms: PTH(1-84), rPTH(1-84)