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Candesartan cilexetil
go.drugbank.com/drugs/DB00796ApprovedInvestigationalIt is administered orally as the prodrug, candesartan cilexetil, which is rapidly converted to its active metabolite, candesartan, during absorption in the gastrointestinal tract. … It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease.
Mixtures: Ag-candesartan HCT, Ag-candesartan HCTCategories: Angiotensin II receptor antagonists, Angiotensin II Antagonists and DiureticsIpilimumab
go.drugbank.com/drugs/DB06186ApprovedInvestigationalIpilimumab is a fully humanized IgG1 monoclonal antibody that blocks cytotoxic T lymphocyte antigen-4 (CTLA-4). … [L12126] Blocking CTLA-4 removes an inhibitory signal from reducing the activity of T lymphocytes.[A35065,A35080,L12126] Ipilimumab was developed by Bristol-Myers Squibb and Medarex.
Categories: Immunoglobulin G, CTLA-4-directed Blocking AntibodyProducts: YERVOY 200MG/40ML IV INFUZYONLUK ÇOZELTI KONSANTRESI ICEREN FLAKON, 1 ADET, YERVOY 50MG/10ML IV INFUZYONLUK ÇOZELTI KONSANTRESI ICEREN FLAKON, 1 ADETNivolumab
go.drugbank.com/drugs/DB09035ApprovedInvestigationalNivolumab is a fully human IgG4 antibody targeting the immune checkpoint programmed death receptor-1 (PD-1). … [L12129] It is also available in combination with [relatlimab] under the brand name Opdualag.[L41265,L49996,L50001]
Mixtures: OPDUALAG® SOLUCION INYECTABLECategories: PD-1/PDL-1 (Programmed cell death protein 1/death ligand 1) inhibitors, PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitorsValine, Leucine, and Isoleucine Degradation
smpdb.ca/view/SMP0000032MetabolicThe first step in each case is a transamination using a single BCAA aminotransferase, with α-ketoglutarate as the amine acceptor. … In muscle, the final products of leucine, isoleucine, and valine catabolism can be fully oxidized via the citric acid cycle; in the liver, they can be directed toward the synthesis of ketone bodies (acetoacetate
Enzymes: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrialIobenguane
go.drugbank.com/drugs/DB06704ApprovedInvestigationalIodine 123 is a cyclotron-produced radionuclide that decays to Te 123 by electron capture. Images are produced by a I123 MIBG scintigraphy. FDA approved on September 19, 2008.
Salts: Iobenguane I 123, Iobenguane I 131Categories: Compounds used in a research, industrial, or household settingCysteinamide
go.drugbank.com/drugs/DB03275InvestigationalSynonyms: 2-amino-3-mercapto-propionamide, L-Cysteinamide2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACID
go.drugbank.com/drugs/DB06862ExperimentalSynonyms: 2-HYDROXY-5-(2-MERCAPTO-ETHYLSULFAMOYL)-BENZOIC ACIDZinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approvedIt is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity. … More information about Zinc (in its natural form) is available at [DB01593].
Mixtures: Evc Liquid Vitamins A,c,b6 With Beta Caro&zn, A+ Zinc TabProducts: ZINC INJECTABLE A 1mg/ml, solution injectable pour perfusion, Zink Aguettant 1 mg/ml Konzentrat zur Herstellung einer InfusionslösungHigh risk, in situ Non-Muscle Invasive Bladder Cancer (NMIBC) Refractory to BCG
go.drugbank.com/conditions/DBCOND0144300Drugs: PembrolizumabSynonyms: High risk, in situ Non-Muscle Invasive Bladder Cancer (NMIBC) Refractory to BCGPrevention of subtype B viruses contained in the 2015 formula Influenza B Virus Infection
go.drugbank.com/conditions/DBCOND0112775Synonyms: Prevention of subtype B viruses contained in the 2015 formula Influenza B Virus Infection