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Dextroamphetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126994Drug actionDextroamphetamine, known commonly as Adderall, is a drug related to amphetamine and is used mainly for treating ADHD and narcolepsy. The drug was approved by the FDA in 2001 for treating ADHD, but the exact mechanisms for its effects are...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Benzphetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126989Drug actionBenzphetamine, commonly known as Didrex, is a sympathomimetic used to treat exogenous obesity. It has properties similar to dextroamphetamine. This drug can be used as a short-term treatment of obesity when combined with altered lifestyl...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Duloxetine SNRI - Dopamine Norepinephrine Inhibition Action Pathway
smpdb.ca/view/SMP0126450Drug actionDuloxetine is a serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence. It blocks both sodium dependent serotonin and sodium dependent norepinephr...
Enzymes: Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortLisdexamfetamine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126990Drug actionLisdexamfetamine, known commonly as Vyvanse, is a prodrug of amphetamine paired with lysine and used mainly for treating ADHD and binge eating disorders. The drug was engineered to be abuse-resistant with a delayed release. ADHD is cause...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Serdexmethylphenidate Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0127003Drug actionSerdexmethylphenidate, known commonly combined with dexmethylphenidate as Azstarys, is a prodrug of dexmethylphenidate (CNS stimulant) used for first-line treatment of ADHD. ADHD is caused by an abnormality in the dopamine transporter ge...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1Arformoterol Action Pathway
smpdb.ca/view/SMP0126088Drug actionArformoterol is a beta-2 adrenergic receptor agonist that is used as a bronchodilator to treat COPD and chronic bronchitis. It accomplishes this by upon inhalation of the drug by relaxing smooth muscles in the airways to improve breathin...
Drugs: ATP · Arformoterol · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphateEnzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Olodaterol Action Pathway
smpdb.ca/view/SMP0126091Drug actionOlodaterol is a beta-2 adrenergic agonist that is long acting. It is used for the management of chronic bronchitis and COPD, but not asthma. It accomplishes this by mediating smooth muscle relaxation and bronchodilator via L-type calcium...
Drugs: ATP · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate · OlodaterolEnzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Procaterol Action Pathway
smpdb.ca/view/SMP0126094Drug actionProcaterol is a beta-2 adrenergic agonist that is used as a bronchodilator. It is a long acting and potent drug that can be taken orally or through inhalation for the treatment of asthma and COPD. The purpose of this drug is to increase ...
Drugs: ATP · Potassium cation · Procaterol · Calcium · Magnesium cation · Cyclic adenosine monophosphateEnzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12Gs Histaminic Smooth Muscle Relaxation
smpdb.ca/view/SMP0126967PhysiologicalThe Gs alpha subunit (Gαs, Gsα) is a subunit of the heterotrimeric G protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase. Gsα is a GTPase that functions as a cellular signaling protein. Gsα is the foundin...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms shortVanoxerine Dopamine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126997Drug actionVanoxerine is an investigational drug that is a selective dopamine transporter antagonist that has not been approved for therapeutic use but is indicated to help treat cocaine addiction. It was developed as a treatment for depression but...
Enzymes: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1