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Displaying results 1551 - 1560 of 3388 in total
  1. Target

    Maltoporin

    go.drugbank.com/bio_entities/BE0003212
    TargetTransporterEscherichia coli (strain K12)

    Also acts as a receptor for several bacteriophages including lambda (PubMed:4201774). Binds maltosaccharides; when LamB binds starch in soft agar, it inhibits motility (PubMed:2832377).

    Synonyms: Lambda receptor protein, Phage lambda receptor protein
  2. Target

    Guanylyl cyclase C

    go.drugbank.com/bio_entities/BE0003502
    TargetHumans

    Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C (PubMed:1680854, PubMed:1718270).

    Synonyms: STA receptor, Heat-stable enterotoxin receptor
  3. Target

    Prohibitin-2

    go.drugbank.com/bio_entities/BE0009007
    TargetHumans

    Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcrip...

    Synonyms: B-cell receptor-associated protein BAP37, Repressor of estrogen receptor activity
  4. Target

    ATP-binding cassette sub-family C member 8

    go.drugbank.com/bio_entities/BE0000207
    TargetTransporterHumans

    Regulator subunit of pancreatic ATP-sensitive potassium channel (KATP), playing a major role in the regulation of insulin release. In pancreatic cells, it forms KATP channels with KCNJ11; KCNJ11 forms the channel pore while ABCC8 is requ...

    Synonyms: Sulfonylurea receptor 1
  5. Drug

    Benzocaine

    go.drugbank.com/drugs/DB01086
    ApprovedInvestigational

    Benzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. It is commonly used for local anesthesia in many over the counter products. Benzocaine was first used for l...

    Mixtures: SUFREXAL P, PM Toothache ReliefCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  6. Target

    Intercellular adhesion molecule 1

    go.drugbank.com/bio_entities/BE0001085
    TargetHumans

    Also functions as a ligand receptor of the signaling receptor ITGAM:ITGB2/MAC-1 ensuring adhesion between stimulated neutrophils and stimulated endothelial cells (PubMed:1980124). … Cell adhesion molecule that functions as a receptor ligand of the signaling receptor ITGAL:ITGB2/LFA-1 (lymphocyte-function associated (LFA) molecule 1) ensuring leukocyte cell-cell adhesion, by providing

    Synonyms: Major group rhinovirus receptor
  7. Drug

    Camphor

    go.drugbank.com/drugs/DB01744
    ApprovedInvestigationalWithdrawn

    Camphor is a bicyclic monoterpene ketone found widely in plants, especially Cinnamomum camphora. It is used topically as a skin antipruritic and as an anti-infective agent. When ingested, camphor has a rapid onset of toxic effects, and c...

    Mixtures: Sarna P, Pain Relieving Po Tong Oil
  8. Target

    CD27 antigen

    go.drugbank.com/bio_entities/BE0010071
    TargetHumans

    Costimulatory immune-checkpoint receptor expressed at the surface of T-cells, NK-cells and B-cells which binds to and is activated by its ligand CD70/CD27L expressed by B-cells (PubMed:28011863).

    Synonyms: CD27L receptor, Tumor necrosis factor receptor superfamily member 7
  9. Drug

    Tilidine

    go.drugbank.com/drugs/DB13787
    Investigational

    Mixtures: TILIDIN 100/8 RETARD 1A PH, TILIDIN 100/8 RETARD 1A PHCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
  10. Target

    Nectin-4

    go.drugbank.com/bio_entities/BE0009798
    TargetHumans

    Does not act as receptor for alpha-herpesvirus entry into cells

    Synonyms: Ig superfamily receptor LNIR, Poliovirus receptor-related protein 4