Search
Trimetazidine
go.drugbank.com/drugs/DB09069ApprovedInvestigational[A233255,A233260] Acidic conditions, caused by anaerobic metabolism and fatty acid oxidation, in response to myocardial ischemia, activate sodium-hydrogen and sodium-calcium antiport systems. … [A233215] It is hypothesized that trimetazidine inhibits 3-ketoacyl coenzyme A thiolase, which decreases fatty acid oxidation but not glucose metabolism, preventing the acidic conditions that exacerbate
Products: AXINOL TABLET 20MG, Metazine Tablet 20mgBortezomib
go.drugbank.com/drugs/DB00188ApprovedInvestigational[A204083] In May 2003, bortezomib became the first anticancer proteasome inhibitor that was approved by the FDA under the trade name VELCADE. … Bortezomib is a dipeptide boronic acid derivative and proteasome inhibitor used to treat multiple myeloma and mantle cell lymphoma.
Categories: Antineoplastic and Immunomodulating AgentsSynonyms: N-[(1R)-1-(DIHYDROXYBORYL)-3-methylbutyl]-N-(pyrazin-2-ylcarbonyl)-L-phenylalaninamideTaurine
go.drugbank.com/drugs/DB01956ApprovedInvestigationalNutraceutical[A31396] This conditional amino acid can be either be manufactured by the body or obtained in the diet mainly by the consumption of fish and meat. … [L1058] The supplements containing taurine were FDA approved by 1984 and they are hypertonic injections composed by cristalline amino acids.[FDA label]
Mixtures: Primene 10%-liq IV, AMINOMIX 1 NOVUM IV INFUZYON ICIN STERIL APIROJEN COZELTI 2000 MLCategories: Amino Acids, Peptides, and ProteinsAcetylcholine
go.drugbank.com/drugs/DB03128ApprovedInvestigationalIt is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, but it is useful in some ophthalmological applications. … Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in
Categories: Antiglaucoma Preparations and MioticsProducts: Miogan Pws 20mg/vialSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)
go.drugbank.com/bio_entities/BE0000423TargetTransporterHumansCan also transport carnitine, butirylcarnitine and propionylcarnitine coupled to the transmembrane gradients of Na(+) and Cl(-) (PubMed:17855766) … Amino acid transporter that plays an important role in the absorption of amino acids in the intestinal tract.
Polypeptides: Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)Polatuzumab vedotin
go.drugbank.com/drugs/DB12240ApprovedInvestigational[L6658] Polatuzumab vedotin was granted accelerated FDA approval on June 10, 2019 [A254936] and was approved by Health Canada on July 9, 2020.[L44141] … Polatuzumab vedotin is a CD79b-directed antibody-drug conjugate that delivers monomethyl auristatin E (MMAE), an anti-mitotic agent, to cancer cells.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsProducts: POLIVY POWDER FOR CONCENTRATE FOR SOLUTION FOR INFUSION 140MG, POLIVY 140mg Powder For Concentrate For Solution For InfusionBone and Joint Infections
go.drugbank.com/conditions/DBCOND0051086Synonyms: Bone and joint infection, Bone and Joint InfectionsCirculatory collapse and shock
go.drugbank.com/conditions/DBCOND0025070Drugs: DopamineSynonyms: Circulatory collapse and shockFriction and Pressure Injuries
go.drugbank.com/conditions/DBCOND0052518Drugs: Fluocinolone acetonideSynonyms: Friction and Pressure Injuries