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Displaying results 1571 - 1580 of 1709 in total
  1. Target

    P2Y purinoceptor 2

    go.drugbank.com/bio_entities/BE0002401
    TargetHumans

    Receptor for ATP and UTP coupled to G proteins that activate a phosphatidylinositol-calcium second messenger system. The affinity range is UTP = ATP > ATP-gamma-S >> 2-methylthio-ATP = ADP

    Synonyms: ATP receptor, P2U receptor 1Function: A1 adenosine receptor binding
  2. Drug

    Beta carotene

    go.drugbank.com/drugs/DB06755
    ApprovedNutraceutical

    Beta-carotene, with the molecular formula C40H56, belongs to the group of carotenoids consisting of isoprene units. The presence of long chains of conjugated double bonds donates beta-carotene with specific colors. It is the most abundan...

    Mixtures: Eden With Vitamins A, C, and E, Multi-Nate 30
  3. Drug

    VA-MENGOC-BC®

    go.drugbank.com/drugs/DB15800
    Experimental

    The OMVs contain over 100 proteins, and are derived from meningococcal group B and capsular polysaccharide of meningococcal group C.

  4. Target

    Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1

    go.drugbank.com/bio_entities/BE0004522
    TargetTransporterHumans

    Inositol 1,4,5-trisphosphate-gated calcium channel that, upon inositol 1,4,5-trisphosphate binding, mediates calcium release from the endoplasmic reticulum (ER) (PubMed:10620513, PubMed:27108797). Undergoes conformational changes upon li...

    Synonyms: IP3 receptor isoform 1, Type 1 InsP3 receptor
  5. Target

    Integrin alpha-V

    go.drugbank.com/bio_entities/BE0003576
    TargetHumans

    ITGAV:ITGB3 acts as a receptor for CD40LG (PubMed:31331973). ITGAV:ITGB3 acts as a receptor for IBSP and promotes cell adhesion and migration to IBSP (PubMed:10640428). … ITGAV:ITGB3 acts as a receptor for SNED1 and mediates R-G-D-dependent cell adhesion to SNED1 (PubMed:39713860)

    Synonyms: Vitronectin receptor, Vitronectin receptor subunit alpha
  6. Drug

    Ligelizumab

    go.drugbank.com/drugs/DB11856
    Investigational

    Initial trials of ligelizumab suggest a greater efficacy over its predecessor for the treatment of CSU.[A242367]

  7. Drug

    Pantoprazole

    go.drugbank.com/drugs/DB00213
    ApprovedInvestigational

    [FDA Label] Due to their good safety profile and as several PPIs are available over the counter without a prescription, their current use in North America is widespread.

  8. Target

    Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2

    go.drugbank.com/bio_entities/BE0009594
    TargetHumans

    Inositol 1,4,5-trisphosphate-gated calcium channel that upon inositol 1,4,5-trisphosphate binding transports calcium from the endoplasmic reticulum lumen to cytoplasm. Exists in two states; a long-lived closed state where the channel is ...

    Synonyms: IP3 receptor isoform 2, Type 2 InsP3 receptor
  9. Target

    T-cell surface antigen CD2

    go.drugbank.com/bio_entities/BE0000719
    TargetHumans

    CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the si...

    Synonyms: LFA-3 receptor, Rosette receptor
  10. Target

    Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3

    go.drugbank.com/bio_entities/BE0009595
    TargetHumans

    Inositol 1,4,5-trisphosphate-gated calcium channel that, upon 1D-myo-inositol 1,4,5-trisphosphate binding, transports calcium from the endoplasmic reticulum lumen to cytoplasm, thus releasing the intracellular calcium and therefore parti...

    Synonyms: IP3 receptor isoform 3, Type 3 InsP3 receptor