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Displaying results 151 - 160 of 2727 in total
  1. Pathway

    Clozapine Dopamine Antagonist Action Pathway

    smpdb.ca/view/SMP0126963
    Drug action

    Clozapine is an antipsychotic drug used in treatment resistant schizophrenia and to decrease suicide risk in schizophrenic patients. Clozapine is available as oral tablets. Clozapine is part of a group of drugs known as second-generation...

    Drugs: Pyridoxal phosphate · Tyrosine · Sapropterin · Clozapine · Dopamine · Levodopa +2 more
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1
  2. Pathway

    Trimebutine M3 Receptor Intestine Relaxation Action Pathway

    smpdb.ca/view/SMP0126338
    Drug action

    Trimebutine is suggested to bind to the inactivated state of the calcium channel with high affinity. Reduced calcium influx attenuates membrane depolarization and decrease colon peristalsis.

    Drugs: ATP · Nitric Oxide · Potassium cation · Calcium · Magnesium cation · Cyclic adenosine monophosphate +3 more
    Enzymes: Voltage-dependent L-type calcium channel subunit beta-4, Voltage-dependent P/Q-type calcium channel subunit alpha-1A
  3. Pathway

    Phenytoin Action Pathway (New)

    smpdb.ca/view/SMP0126264
    Drug action

    Phenytoin is an anticonvulsant drug used in the prophylaxis and control of various types of seizures. It can be found under the brand names Dilantin and Phenytek. Although phenytoin first appeared in the literature in 1946, it has taken ...

    Drugs: Phenytoin · Potassium cation · Calcium
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent T-type calcium channel subunit alpha-1G
  4. Pathway

    Fenethazine H1-Antihistamine Action

    smpdb.ca/view/SMP0059707
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Calcium
  5. Pathway

    Temelastine H1-Antihistamine Action

    smpdb.ca/view/SMP0062880
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Calcium
  6. Pathway

    Bamipine H1-Antihistamine Action

    smpdb.ca/view/SMP0062882
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Calcium
  7. Pathway

    Pyrrobutamine H1-Antihistamine Action

    smpdb.ca/view/SMP0062887
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Calcium
  8. Pathway

    Phospholipase C Signaling Pathway

    smpdb.ca/view/SMP0063783
    Signaling

    IP3 releases calcium from the endoplasmic reticulum. PIP3 is an important regulator of AKT signaling and downstream pathways.

    Drugs: Calcium
  9. Pathway

    Muscular Gq Protien Cascade

    smpdb.ca/view/SMP0126980
    Physiological

    through calcium binding proteins and calcium-sensitive processes. … These channels are specific to calcium and only allow the passage of calcium from the ER into the cytoplasm.

    Drugs: Calcium
  10. Pathway

    Doxylamine H1-Antihistamine Immune Response Action Pathway

    smpdb.ca/view/SMP0058803
    Drug action

    Furthermore, lowering calcium ion concentration leads to increased mast cell stability which reduces further histamine release.

    Drugs: Doxylamine · Calcium
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent L-type calcium channel subunit beta-1