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Zinc acetate

Coal tar

Coal tar is among the by-products when coal is carbonized to make coke or gasified to make coal gas. … It has been indicated for local relief of itching, dryness, and irritation caused by psoriasis, seborrhea and eczema.

Fondaparinux

The monomeric sequence in heparin and HS is thought to form the high affinity binding site for the natural anti-coagulant factor, antithrombin III (ATIII). … Once bound to heparin or HS, the anticoagulant activity of ATIII is potentiated by 1000-fold. Fondaparinux potentiates the neutralizing action of ATIII on activated Factor X 300-fold.

Estrone

Estrone may be further metabolized to 16-alpha-hydroxyestrone, which may be reduced to estriol by estradiol dehydrogenase. … It is produced in vivo from androstenedione or from testosterone via estradiol.

Bisacodyl

[A233300,L13362] Both bisacodyl and [picosulfate] are metabolized to the same active metabolite bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM). … [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]

Nalbuphine

It appears to be an agonist at kappa opioid receptors and an antagonist or partial agonist at mu opioid receptors.

Loratadine

Loratadine is a second generation antihistamine used to manage symptoms of allergic rhinitis.

Propylthiouracil

(From Martindale, The Extra Pharmacopeoia, 30th ed, p534) … Propythiouracil inhibits the synthesis of thyroxine and inhibits the peripheral conversion of throxine to tri-iodothyronine. It is used in the treatment of hyperthyroidism.

Drospirenone

[L33199,L33174] Aside from its contraceptive effects, drospirenone is used with estrogens to control acne and premenstrual dysphoric disorder (PMDD). … Some studies have demonstrated a significantly increased risk and some demonstrating no risk of thromboembolic events.