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Displaying results 1631 - 1640 of 10000 in total
  1. Drug

    Iopofosine I-131

    go.drugbank.com/drugs/DB15244
    Investigational

    Iopofosine I-131 (NM-404 I-131) is under investigation in clinical trial NCT01495663 (Dose Escalation Study of I-131-CLR1404 in Subjects With Cancer That Does Not Respond to Treatment or Has Returned).

    Synonyms: Ethanaminium, 2-((hydroxy((18-(4-(iodo-131I)phenyl)octadecyl)oxy)phosphinyl)oxy)-N,N,N-trimethyl-, inner salt, 2-((HYDROXY((18-(4-(131I)IODOPHENYL)OCTADECYL)OXY)PHOSPHINYL)OXY)-N,N,NTRIMETHYLETHANAMINIUM INNER SALT
  2. Drug

    Tralokinumab

    go.drugbank.com/drugs/DB12169
    ApprovedInvestigational

    US in December 2021. … [A242432] It is estimated to affect up to 20% of adults and children worldwide, and is frequently associated with other atopic conditions such as asthma or allergic rhinitis.

    Categories: Agents for Dermatitis, Excluding Corticosteroids
  3. Indication

    Uterine Hemorrhage

    go.drugbank.com/conditions/DBCOND0035247
    Drugs: Methylergometrine
    Synonyms: Hemorrhage in uterus, Haemorrhage in uterus
  4. Indication

    Blast phase Chronic myeloid leukemia

    go.drugbank.com/conditions/DBCOND0023499
    Drugs: Bosutinib · Cytarabine · Dasatinib · Imatinib · Ponatinib
    Synonyms: Chronic Myelogenous Leukemia in Blast Crisis, Chronic Myelogenous Leukemia (CML) in Blast Crisis
  5. Drug

    Oxaloacetic acid

    go.drugbank.com/drugs/DB16921
    Investigational

    Synonyms: Oxalacetic acid trans-(z)-enol form
  6. Indication

    HIV Wasting Syndrome

    go.drugbank.com/conditions/DBCOND0000270
    Drugs: Somatotropin
    Synonyms: HIV disease resulting in wasting syndrome
  7. Drug

    Odevixibat

    go.drugbank.com/drugs/DB16261
    ApprovedInvestigational

    [A236808,L34793] Odevixibat is the first approved non-surgical treatment option for PFIC.[L34803] Previous therapies for PFIC included a bile acid sequestrant such as [ursodeoxycholic acid]. … Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC

  8. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    Based on this uncertainty, in 2009, the FDA ultimately rejected Cell Therapeutic's initial application for accelerated approval for pixantrone use in relapsed or refractory NHL. … Another phase III trial, PIX-R, is now ongoing to clarify pixantrones place in therapy. It will compare pixantrone efficacy to that of gemcitabine. [2]

    Categories: Topoisomerase II Inhibitors
  9. Drug

    Tamsulosin

    go.drugbank.com/drugs/DB00706
    ApprovedInvestigational

    [Label] Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor muscles in the bladder, allowing for better urinary flow. … [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.

    Categories: Drugs Used in Benign Prostatic HypertrophySynonyms: (R)-(−)-tamsulosin, (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
  10. Drug

    Vibegron

    go.drugbank.com/drugs/DB14895
    ApprovedInvestigational

    On December 23, 2020, vibegron was approved for the same indication in adults. It is available as oral tablets under the market name GEMTESA. … [L28305] Vibegron was first approved in Japan in September 2018 for the treatment of overactive bladder,[A226050] a condition associated with distressing symptoms of urge urinary incontinence, urgency,

    Categories: Drugs for Urinary Frequency and Incontinence