Search

Displaying results 1631 - 1640 of 10000 in total
  1. Indication

    Blast phase Chronic myeloid leukemia

    go.drugbank.com/conditions/DBCOND0023499
    Drugs: Bosutinib · Cytarabine · Dasatinib · Imatinib · Ponatinib
    Synonyms: Chronic Myelogenous Leukemia in Blast Crisis, Chronic Myelogenous Leukemia (CML) in Blast Crisis
  2. Drug

    Anakinra

    go.drugbank.com/drugs/DB00026
    ApprovedInvestigational

    [L35415] Anakinra is indicated for the management of rheumatoid arthritis (RA) in patients 18 years of age or older who have failed one or more disease-modifying antirheumatic drugs (DMARDs), as well as … [A247265] On November 8, 2022, the FDA issued an emergency use authorization (EUA) of anakinra for the treatment of COVID-19 in hospitalized patients who are at risk of progressing to severe respiratory

    Categories: Biologics for Rheumatoid Arthritis TreatmentSynonyms: IL-1RA
  3. Drug

    Oxaloacetic acid

    go.drugbank.com/drugs/DB16921
    Investigational

    Synonyms: Oxalacetic acid trans-(z)-enol form
  4. Indication

    HIV Wasting Syndrome

    go.drugbank.com/conditions/DBCOND0000270
    Drugs: Somatotropin
    Synonyms: HIV disease resulting in wasting syndrome
  5. Drug

    Odevixibat

    go.drugbank.com/drugs/DB16261
    ApprovedInvestigational

    [A236808,L34793] Odevixibat is the first approved non-surgical treatment option for PFIC.[L34803] Previous therapies for PFIC included a bile acid sequestrant such as [ursodeoxycholic acid]. … Odevixibat, or A4250, is an ileal sodium/bile acid cotransporter inhibitor indicated for the treatment of pruritus in patients older than 3 months, with progressive familial intrahepatic cholestasis (PFIC

  6. Drug

    Pixantrone

    go.drugbank.com/drugs/DB06193
    ApprovedWithdrawn

    Based on this uncertainty, in 2009, the FDA ultimately rejected Cell Therapeutic's initial application for accelerated approval for pixantrone use in relapsed or refractory NHL. … Another phase III trial, PIX-R, is now ongoing to clarify pixantrones place in therapy. It will compare pixantrone efficacy to that of gemcitabine. [2]

    Categories: Topoisomerase II Inhibitors
  7. Drug

    Tamsulosin

    go.drugbank.com/drugs/DB00706
    ApprovedInvestigational

    [Label] Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor muscles in the bladder, allowing for better urinary flow. … [Label] It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy.

    Synonyms: (R)-(−)-tamsulosin, (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamideCategories: Drugs Used in Benign Prostatic Hypertrophy
  8. Drug

    Vibegron

    go.drugbank.com/drugs/DB14895
    ApprovedInvestigational

    On December 23, 2020, vibegron was approved for the same indication in adults. It is available as oral tablets under the market name GEMTESA. … [L28305] Vibegron was first approved in Japan in September 2018 for the treatment of overactive bladder,[A226050] a condition associated with distressing symptoms of urge urinary incontinence, urgency,

    Categories: Drugs for Urinary Frequency and Incontinence
  9. Target

    G protein-coupled bile acid receptor 1

    go.drugbank.com/bio_entities/BE0005788
    TargetHumans

    G protein-coupled receptor for bile acid (PubMed:12419312, PubMed:12524422, PubMed:32698187, PubMed:32747649, PubMed:35858343). … Involved in bile acid promoted GLP-1 secretion (By similarity)

    Synonyms: Membrane-type receptor for bile acids
  10. Drug

    Clotiazepam

    go.drugbank.com/drugs/DB01559
    ApprovedIllicit

    Clotiazepam is a thienodiazepine, not approved for sale in the U.S. or Canada, but has been approved in the U.K. It is a schedule IV drug in Canada.