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Displaying results 1681 - 1690 of 8696 in total
  1. Target

    Glutamate receptor 1

    go.drugbank.com/bio_entities/BE0000640
    TargetHumans

    L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. … The receptor then desensitizes rapidly and enters in a transient inactive state, characterized by the presence of bound agonist (By similarity).

    Polypeptides: Glutamate receptor 1Synonyms: AMPA-selective glutamate receptor 1, Glutamate receptor ionotropic, AMPA 1
  2. Target

    Vitamin D3 receptor

    go.drugbank.com/bio_entities/BE0000779
    TargetHumans

    Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR (PubMed:28698609). … Also functions as a receptor for the secondary bile acid lithocholic acid (LCA) and its metabolites (PubMed:12016314, PubMed:32354638)

    Polypeptides: Vitamin D3 receptorSynonyms: 1,25-dihydroxyvitamin D3 receptor, Nuclear receptor subfamily 1 group I member 1
  3. Target

    Estrogen receptor beta

    go.drugbank.com/bio_entities/BE0000792
    TargetHumans

    Nuclear hormone receptor.

    Polypeptides: Estrogen receptor betaSynonyms: Nuclear receptor subfamily 3 group A member 2
  4. Target

    Glutamate receptor 2

    go.drugbank.com/bio_entities/BE0000829
    TargetHumans

    L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system and plays an important role in fast excitatory synaptic transmission (PubMed:14687553). … The receptor then desensitizes rapidly and enters in a transient inactive state, characterized by the presence of bound agonist (By similarity).

    Polypeptides: Glutamate receptor 2Synonyms: AMPA-selective glutamate receptor 2, Glutamate receptor ionotropic, AMPA 2
  5. Target

    Glutamate receptor 3

    go.drugbank.com/bio_entities/BE0000831
    TargetHumans

    L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system and plays an important role in fast excitatory synaptic transmission by inducing long-term potentiation … The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:17989220).

    Polypeptides: Glutamate receptor 3Synonyms: AMPA-selective glutamate receptor 3, Glutamate receptor ionotropic, AMPA 3
  6. Target

    Adrenocorticotropic hormone receptor

    go.drugbank.com/bio_entities/BE0000848
    TargetHumans

    G protein-coupled receptor for corticotropin/ACTH, primarily expressed in adrenal cortex where it plays a key role in the regulation of adrenocortical function (PubMed:1325670, PubMed:17596328, PubMed:

    Polypeptides: Adrenocorticotropic hormone receptorSynonyms: ACTH receptor, Melanocortin receptor 2
  7. Target

    Adenosine receptor A2a

    go.drugbank.com/bio_entities/BE0000924
    TargetHumans

    Receptor for adenosine (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity)

    Polypeptides: Adenosine receptor A2a
  8. Target

    Substance-K receptor

    go.drugbank.com/bio_entities/BE0002222
    TargetHumans

    Substance K binding to its receptor triggers G protein-coupled receptor signaling via activation of G(q) and phosphatidylinositol hydrolysis by phospholipase C (PubMed:7957923, PubMed:35882833). … This is a receptor for the tachykinin neuropeptide substance K (neurokinin A) (PubMed:1659297, PubMed:1848773).

    Polypeptides: Substance-K receptorSynonyms: NK-2 receptor, Neurokinin A receptor
  9. Target

    KiSS-1 receptor

    go.drugbank.com/bio_entities/BE0003468
    TargetHumans

    Receptor for kisspeptins (kisspeptin-10, kisspeptin-13, kisspeptin-14 and metastin/kisspeptin-54) (PubMed:11457843, PubMed:11527393, PubMed:15020672, PubMed:15596153). … In these neurons, kisspeptin binding to its receptor activates G(q)-dependent signaling, leading to phospholipase C (PLC) activation, and hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) (PubMed

    Polypeptides: KiSS-1 receptorSynonyms: Metastin receptor, Kisspeptins receptor
  10. Target

    Aryl hydrocarbon receptor

    go.drugbank.com/bio_entities/BE0003721
    TargetHumans

    Ligand-activated transcription factor that enables cells to adapt to changing conditions by sensing compounds from the environment, diet, microbiome and cellular metabolism, and which plays important roles in development, immunity and ca...

    Polypeptides: Aryl hydrocarbon receptorSynonyms: Ah receptor