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Displaying results 161 - 170 of 6222 in total
  1. Target

    Voltage-dependent P/Q-type calcium channel subunit alpha-1A

    go.drugbank.com/bio_entities/BE0000356
    TargetHumans

    Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone … The isoform alpha-1A gives rise to P and/or Q-type calcium currents.

    Polypeptides: Voltage-dependent P/Q-type calcium channel subunit alpha-1ASynonyms: Brain calcium channel I, Voltage-gated calcium channel subunit alpha Cav2.1
  2. Target

    Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A

    go.drugbank.com/bio_entities/BE0003565
    TargetHumans

    Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes.

    Polypeptides: Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
  3. Target

    Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C

    go.drugbank.com/bio_entities/BE0009596
    TargetHumans

    Calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:29860631, PubMed:8557689). Has a high af...

    Polypeptides: Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
  4. Target

    Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B

    go.drugbank.com/bio_entities/BE0003323
    TargetHumans

    Cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes (PubMed:15260978, PubMed:8855339, PubMed:9419816). Has a preference f...

    Polypeptides: Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
  5. Target

    Inositol 1,4,5-trisphosphate receptor

    go.drugbank.com/bio_entities/BE0004914
    TargetHumans

    thus providing calcium for the downstream calcium channel MCU that directly releases it into mitochondria matrix (By similarity). … Inositol 1,4,5-trisphosphate-gated calcium channel that upon inositol 1,4,5-trisphosphate binding transports calcium from the endoplasmic reticulum lumen to cytoplasm.

    Polypeptides: Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1, Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2Function: calcium ion binding, calcium channel inhibitor activity
  6. Target

    Calcineurin B homologous protein 1

    go.drugbank.com/bio_entities/BE0008693
    TargetHumans

    Inhibits both STK17B auto- and substrate-phosphorylations in a calcium-dependent manner … Inhibits NFAT nuclear translocation and transcriptional activity by suppressing the calcium-dependent calcineurin phosphatase activity.

    Synonyms: Calcium-binding protein CHP, Calcium-binding protein p22Function: calcium ion binding
  7. Target

    Transient receptor potential cation channel subfamily V member 6

    go.drugbank.com/bio_entities/BE0005102
    TransporterTargetHumans

    The channel is activated by low internal calcium level, probably including intracellular calcium store depletion, and the current exhibits an inward rectification (PubMed:15184369). … Calcium selective cation channel that mediates Ca(2+) uptake in various tissues, including the intestine (PubMed:11097838, PubMed:11248124, PubMed:11278579, PubMed:15184369, PubMed:23612980, PubMed:29258289

    Synonyms: Calcium transport protein 1, Epithelial calcium channel 2Function: calcium channel activity
  8. Target

    Calpain small subunit 1

    go.drugbank.com/bio_entities/BE0004144
    TargetHumans

    Regulatory subunit of the calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

    Synonyms: Calcium-dependent protease small subunit, Calcium-dependent protease small subunit 1Function: calcium ion binding
  9. Target

    Protein S100-A13

    go.drugbank.com/bio_entities/BE0000885
    TargetHumans

    Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. … The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine (By similarity)

    Synonyms: S100 calcium-binding protein A13Function: calcium ion binding
  10. Target

    Guided entry of tail-anchored proteins factor CAMLG

    go.drugbank.com/bio_entities/BE0000379
    TargetHumans

    Stimulates calcium signaling in T cells through its involvement in elevation of intracellular calcium (PubMed:7522304). Essential for the survival of peripheral follicular B cells (By similarity)

    Synonyms: Calcium signal-modulating cyclophilin ligand