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Displaying results 1691 - 1700 of 1709 in total
  1. Target

    Lysosome membrane protein 2

    go.drugbank.com/bio_entities/BE0014604
    TransporterHumans

    Acts as a lysosomal receptor for glucosylceramidase (GBA1) targeting

    Synonyms: Scavenger receptor class B member 2Function: cargo receptor activity
  2. Target

    Cytohesin-3

    go.drugbank.com/bio_entities/BE0004433
    TargetHumans

    Promotes guanine-nucleotide exchange on ARF1 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays a role in the epithelial polarization (By similarity)

    Synonyms: General receptor of phosphoinositides 1
  3. Target

    Elongation factor 1-alpha 1

    go.drugbank.com/bio_entities/BE0004528
    TargetHumans

    Translation elongation factor that catalyzes the GTP-dependent binding of aminoacyl-tRNA (aa-tRNA) to the A-site of ribosomes during the elongation phase of protein synthesis (PubMed:26593721, PubMed:26651998, PubMed:36123449, PubMed:362...

    Synonyms: Leukocyte receptor cluster member 7
  4. Target

    C-type lectin domain family 7 member A

    go.drugbank.com/bio_entities/BE0019143
    TargetHumans

    Lectin that functions as a pattern recognizing receptor (PRR) specific for beta-1,3-linked and beta-1,6-linked glucans, which constitute cell wall constituents from pathogenic bacteria and fungi (PubMed

    Synonyms: Beta-glucan receptor
  5. Target

    COUP transcription factor 1

    go.drugbank.com/bio_entities/BE0008953
    TargetHumans

    Coup (chicken ovalbumin upstream promoter) transcription factor binds to the ovalbumin promoter and, in conjunction with another protein (S300-II) stimulates initiation of transcription. Binds to both direct repeats and palindromes of th...

    Synonyms: Nuclear receptor subfamily 2 group F member 1
  6. Target

    Retinoic acid-induced protein 3

    go.drugbank.com/bio_entities/BE0000697
    TargetHumans

    Orphan receptor. Could be involved in modulating differentiation and maintaining homeostasis of epithelial cells.

    Synonyms: G protein-coupled receptor family C group 5 member A
  7. Target

    VLA-4 (very late antigen-4)

    go.drugbank.com/bio_entities/BE0010014
    TargetHumans

    Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. … Integrin alpha-4/beta-7 is also a receptor for MADCAM1. It recognizes the sequence L-D-T in MADCAM1.

    Synonyms: Fibronectin receptor subunit beta
  8. Target

    NACHT, LRR and PYD domains-containing protein 3

    go.drugbank.com/bio_entities/BE0010347
    TargetHumans

    Sensor component of the NLRP3 inflammasome, which mediates inflammasome activation in response to defects in membrane integrity, leading to secretion of inflammatory cytokines IL1B and IL18 and pyroptosis (PubMed:16407889, PubMed:1840367...

    Synonyms: Angiotensin/vasopressin receptor AII/AVP-like
  9. Target

    Kinesin-like protein KIF11

    go.drugbank.com/bio_entities/BE0001852
    TargetHumans

    Motor protein required for establishing a bipolar spindle and thus contributing to chromosome congression during mitosis (PubMed:19001501, PubMed:37728657). Required in non-mitotic cells for transport of secretory proteins from the Golgi...

    Synonyms: Thyroid receptor-interacting protein 5
  10. Drug

    Cannabidivarin

    go.drugbank.com/drugs/DB14050
    Investigational

    It is one of over 100 cannabinoids identified from the Cannabis plant that can modulate the physiological activity of cannabis, or marijuana [A32584]. … The anti-epileptic activity of CBD and CBDV is thought to be modulated by their effects on transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor