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Rocbrutinib
go.drugbank.com/drugs/DB19445InvestigationalRocbrutinib is under investigation in clinical trial NCT05716087 (A Study of Rocbrutinib in Participants With Relapse or Refractory Mantle Cell Lymphoma).
Synonyms: -2H-pyran-4-yl)-1-piperazinyl]phenyl]-2-propena, 2-Propenamide, N-[5-[[6-[2-(1,3,4,6,7,8-hexahydro-7,7-dimethyl-1-oxo-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-2-yl)-3-(hydroxymethyl)-4-pyridinyl]-3,4-dihydro-4-methyl-3-oxo-2-pyrazinyl]amino]-2-[(2S)-2Fluocinolone acetonide
go.drugbank.com/drugs/DB00591ApprovedInvestigationalVet approved[T358] This type of device containing fluocinolone acetonide was developed by Taro Pharmaceuticals and approved by FDA in May 2016.[L4676] … [T357] It has been used extensively in dermatological preparations and it has also been investigated thoroughly for its use in implantable corticosteroid devices.
Synonyms: acétonide de fluocinolone, acetónido de fluocinolonaInternational brands: Cordes F, Co-FIuosinPolyneuritis
go.drugbank.com/conditions/DBCOND0096968Drugs: CocarboxylaseSynonyms: Other neurologic disorders in Lyme diseaseTizanidine
go.drugbank.com/drugs/DB00697ApprovedInvestigationalInitially approved by the FDA in 1996, tizanidine is an Alpha-2 adrenergic receptor agonist reducing spasticity by the presynaptic inhibition of excitatory neurotransmitters that cause firing of neurons … Tizanidine is a fast-acting drug used for the management of muscle spasm, which may result from the effects of multiple sclerosis, stroke, an acquired brain injury, or a spinal cord injury [T574].
Synonyms: 5-Chloro-4-(2-imidazolin-2-ylamino)-2,1,3-benzothiadiazoleMixtures: ALGI - B® TABLETAS, ALGI - B® TABLETASPrazosin
go.drugbank.com/drugs/DB00457ApprovedInvestigationalPrazosin is a drug used to treat hypertension. Prazosin is marketed by _Pfizer_ and was initially approved by the FDA in 1988. … [L5828] It belongs to the class of drugs known as alpha-1 antagonists.
Synonyms: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine, 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazolineCategories: P-glycoprotein inhibitors, P-glycoprotein substratesPovidone-iodine
go.drugbank.com/drugs/DB06812ApprovedInvestigationalDuring in vitro testing to demonstrate anti-bacterial activity it was found that the complex was less toxic in mice than tincture of iodine. … This unique complex was discovered in 1955 at the Industrial Toxicology Laboratories in Philadelphia by H. A. Shelanski and M. V. Shelanski.
Mixtures: BRAUNODERM (IN 250ML AND 1000ML PLASTIC), Physician EZ Use Joint Tunnel and Trigger Kit IICategories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingEmphysema
go.drugbank.com/conditions/DBCOND0019688Drugs: Albuterol · Alpha-1-proteinase inhibitor · Bambuterol · Carmoterol · Fluticasone propionate · Guaifenesin +2 moreSynonyms: Pathological accumulation of air in tissuesLevosimendan
go.drugbank.com/drugs/DB00922ApprovedInvestigationalWithdrawnLevosimendan is under investigation in clinical trial NCT00527059 (Renal Effects of Levosimendan in Patients Admitted With Acute Decompensated Heart Failure). … Levosimendan increases calcium sensitivity to myocytes by binding to troponin C in a calcium dependent manner. This increases contractility without raising calcium levels.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 1-RingProducts: SİMELEV 12,5 MG/5 ML IV İNFÜZYONLUK ÇÖZELTİ HAZIRLAMAK İÇİN KONSANTRE, 1 ADET, Levosimendan Win Medica 2,5 mg/ml Konzentrat zur Herstellung einer InfusionslösungDiffuse Midline Glioma, H3 K27M-Mutant
go.drugbank.com/conditions/DBCOND0092211Drugs: DordaviproneSynonyms: Diffuse midline glioma, point mutation K27M in histone H3 (morphologic abnormality)