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Hawkinsinuria
smpdb.ca/view/SMP0125590Diseasepyroglutamic acid in urine; and L-tyrosine in plasma. … Symptoms include ketosis, metabolic acidosis, swimming-pool odor, and mental retardation. Treatment includes a low-protein diet and vitamin C.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Tyrosine · Glutamic acid +20 moreAromatic L-Aminoacid Decarboxylase Deficiency
smpdb.ca/view/SMP0125610DiseaseSymptoms include temperature instability, hypotonia, mental and motor retardation, and cerebral atrophy. … A deficiency in this enzyme results in accumulation of 3-methoxytyrosine, 5-hydroxy-L-tryptophan, and L-Dopa in plasma, spinal fluid, and urine; 3-methoxytyramine and dopamine in urine.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Tyrosine · Norepinephrine · Epinephrine +4 moreTrimipramine Action Pathway
smpdb.ca/view/SMP0126348Drug actionIt is very similar to imipramine but it has more antihistaminic and sedative properties. Trimipramine acts by decreasing the reuptake of norepinephrine and serotonin (5-HT) in the neurons. … Trimipramine is a tricyclic antidepressant (TCA) used to treat depression accompanied or not by anxiety and agitation or sleep disturbance.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Tryptophan · Sapropterin · Norepinephrine +7 moreClomipramine Action Pathway (New)
smpdb.ca/view/SMP0126354Drug action, and Tourette’s disorder. … It blocks both sodium-dependent serotonin and sodium-dependent norepinephrine transporters from removing serotonin and norepinephrine respectively from the synaptic clefts in the brain.
Duloxetine SNRI - Dopamine Norepinephrine Inhibition Action Pathway
smpdb.ca/view/SMP0126450Drug actionThe receptors that are being stimulated are 5-HT 2A, 2B, and 2C serotonin receptors and alpha 1 and beta 1 adrenergic receptors. … Stimulation of the 2A, 2B and 3C receptor can increase cognitive abilities like learning, appetite, memory, mood and sleep.
Methylphenidate Norepinephrine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126572Drug actionNorepinephrine is then transported to the prefrontal cortex and released into the synapse when the neuron is stimulated and fires. … This helps people with ADHD to sustain attention and working memory.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · ATP · Norepinephrine · Methylphenidate +7 moreMethamphetamine Norepinephrine Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126618Drug actionThese cascades help regulate memory and attention. … This causes increased heartrate, increased blood pressure caused by vasoconstriction, increased breathing rate, and decreased appetite and digestion.
Drugs: Pyridoxal phosphate · Ascorbic acid · Tyrosine · Norepinephrine · Dopamine · Levodopa +4 moreAmine Oxidase Norepinephrine
smpdb.ca/view/SMP0130460Physiological) as well as toxins and carcinogens in foods and the environment. … The first one is found in cells located in the periphery and breakdown serotonin, norepinephrine, epinephrine, dopamine, and tyramine.
Tyrosine Metabolism
smpdb.ca/view/SMP0000006MetabolicThyroid hormones are produced and released by the thyroid gland and include triiodothyronine (T3) and thyroxine (T4). These two hormones are responsible for regulating metabolism. … Catecholamines such as L-DOPA, dopamine and methoxytyramine are produced mainly by the chromaffin cells of the adrenal medulla and by neuronal cells found in the brain.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Tyrosine · Glutamic acid +20 moreTyrosinemia, Transient, of the Newborn
smpdb.ca/view/SMP0000494Diseaseand derivatives. … The inhibition is reversible by removal of excess substrate and by reducing agents such as ascorbic acid, 2, 6-dichiorophenolindophenol, and a number of hydroquinone and phenylenediamine compounds.
Drugs: Pyridoxal phosphate · Ademetionine · Ascorbic acid · Aspartic acid · Tyrosine · Glutamic acid +20 more