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Chlordiazepoxide Action Pathway
smpdb.ca/view/SMP0126120Drug actionSome side effects of using chlordiazepoxide may include drowsiness, dizziness, and weakness. … The net neuro-inhibitory effects result in the observed sedative, hypnotic, anxiolytic, and muscle relaxant properties.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Chlordiazepoxide · Calcium · Magnesium cation +3 moreEnzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Flurazepam Action Pathway
smpdb.ca/view/SMP0126129Drug actionusers to drive safely and increase risks of falls and hip fractures. … Some side effects of using flurazepam may include drowsiness, dizziness, headache, and nausea.
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Butalbital Action Pathway
smpdb.ca/view/SMP0126149Drug actionButalbital, or 5-allyl-5-isobutylbarbituric acid, is a derivative of barbituric acid which the hydrogens at position 5 are substituted by an allyl group and an isobutyl group. … Typically indicated to manage tension (or muscle contraction) headaches, butalbital is often combined with one or more therapeutic agents, such as acetylsalicylic acid, acetaminophen, aspirin, and caffeine
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Flumazenil Action Pathway
smpdb.ca/view/SMP0126152Drug actionSome side effects of using flumazenil may include headache, dizziness, nausea, and flushing. … Fumazenil is an imidazobenzodiazepine derivative and a potent benzodiazepine receptor antagonist that competitively inhibits the activity at the benzodiazepine recognition site on the GABA/benzodiazepine
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Halothane GABA(A) Anesthetic Action Pathway
smpdb.ca/view/SMP0126161Drug actionIt also acts as an NMDA receptor antagonist, inhibits nACh and voltage-gated sodium channels, and activates 5-HT3 and twin-pore K+ channels. … It can be found under the brand name Fluothane and the exact mechanism of the action of general anaesthetics has not been delineated. Halothane activates GABAA and glycine receptors.
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Sevoflurane GABA(A) Anesthetic Action Pathway
smpdb.ca/view/SMP0126170Drug actionIt can be found under the brand names Sevorane, Sojourn, and Ultane. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. … The hemodynamic and respiratory depressive effects of sevoflurane are well tolerated, and most patients receiving this anesthetic agent present little toxicity.
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Thiopental Action Pathway
smpdb.ca/view/SMP0126813Drug actionAlthough it lacks excitatory effects, its analgesic and muscle relaxant properties are limited. It has been shown that low doses can counteract analgesia and lower the pain threshold. … for analgesia or muscle relaxation, for managing convulsions during inhalation or local anesthesia, in neurosurgical cases with heightened intracranial pressure, and for narcoanalysis and narcosynthesis
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Zaleplon Action Pathway
smpdb.ca/view/SMP0126830Drug actionFunctioning within the gamma-aminobutyric acid-benzodiazepine (GABABZ) receptor complex, it shares certain pharmacological attributes with benzodiazepines despite its distinct chemical structure. … Zaleplon, distinctly separate from benzodiazepines and other hypnotic agents, effectively addresses short-term insomnia by interacting with these receptor systems.
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Diazepam Action Pathway
smpdb.ca/view/SMP0124471Drug actionDiazepam binds to various regions of the brain and spinal cord where GABA A receptors are. … It binds to an allosteric site between the alpha and gamma subunits of the receptor increasing the inhibitory effects of GABA.
Enzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1Etizolam Action Pathway
smpdb.ca/view/SMP0125057Drug actionIt is an agonist at GABA-A receptors and possesses amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. … anticonvulsant activity, and anxiolytic action.
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Calcium · Magnesium cation · Cyclic adenosine monophosphate +2 moreEnzymes: Gamma-aminobutyric acid type B receptor subunit 2, Gamma-aminobutyric acid receptor subunit alpha-1