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Displaying results 1891 - 1900 of 10000 in total
  1. Target

    Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase

    go.drugbank.com/bio_entities/BE0009519
    TargetHumans

    May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect (PubMed:9001210, PubMed:9268380) … Also involved in Golgi fragmentation (PubMed:9001210, PubMed:9268380).

    Polypeptides: Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase
  2. Target

    Signal transducer and activator of transcription 1-alpha/beta

    go.drugbank.com/bio_entities/BE0010099
    TargetHumans

    Involved in food tolerance in small intestine: associates with the Gasdermin-D, p13 cleavage product (13 kDa GSDMD) and promotes transcription of CIITA, inducing type 1 regulatory T (Tr1) cells in upper … In response to type II IFN (IFN-gamma), STAT1 is tyrosine- and serine-phosphorylated (PubMed:26479788).

    Polypeptides: Signal transducer and activator of transcription 1-alpha/beta
  3. Indication

    Acute naused and vomiting caused by Chemotherapy

    go.drugbank.com/conditions/DBCOND0025637
    Drugs: Netupitant · Palonosetron
    Synonyms: Acute Chemotherapy-Induced Nausea and Vomiting, Acute chemotherapy induced nausea and vomiting
  4. Indication

    Non-complicated Skin and Soft Tissue Infections

    go.drugbank.com/conditions/DBCOND0046572
    Drugs: Teicoplanin
    Synonyms: Non-complicated Skin and Soft Tissue Infections
  5. Indication

    Other and unspecified effects of high altitude

    go.drugbank.com/conditions/DBCOND0024755
    Drugs: Acetazolamide
    Synonyms: Other and unspecified high altitude effects, Other and unspecified effects of high altitude
  6. Indication

    Complicated Skin and subcutaneous tissue bacterial infection

    go.drugbank.com/conditions/DBCOND0025759
    Drugs: Dalfopristin · Quinupristin · Telavancin
    Synonyms: Complicated skin and subcutaneous tissue bacterial infections, Complicated Skin and subcutaneous tissue bacterial infection
  7. Drug

    Serrapeptase

    go.drugbank.com/drugs/DB13131
    Investigational

    Serrapeptase is a proteolytic enzyme preparation used concomitantly with an antibiotic in osteoarticular infections. … Serratiopeptidase is under investigation in clinical trial NCT02493179 (Efficacy Evaluation of the (Serodase 5 mg Tablet) in the Treatment of Inflammation After Third Molar Surgery).

    Categories: Enzymes and CoenzymesProducts: Serrata Tablets 10mg, Tablets 5mg
  8. Drug

    Framycetin

    go.drugbank.com/drugs/DB00452
    ApprovedInvestigational

    A component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed)

    International brands: Leukase NProducts: Soframycin Eye Drops 5mg/ml
  9. Drug

    CAP-1

    go.drugbank.com/drugs/DB08027
    Investigational

  10. Target

    Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

    go.drugbank.com/bio_entities/BE0003558
    TargetHumans

    Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP (PubMed:10725373, PubMed:10906126, PubMed:11050148, PubMed:16330539). … Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively (PubMed:10725373, PubMed:10906126, PubMed:11050148)

    Polypeptides: Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11ASynonyms: cAMP and cGMP phosphodiesterase 11A