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Voltage-gated potassium channel KCNC2
go.drugbank.com/bio_entities/BE0004724TargetHumans, slowing channel activation and deactivation of delayed rectifier potassium channels (By similarity). … Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain.
Polypeptides: Voltage-gated potassium channel KCNC2Synonyms: Shaw-like potassium channel, Voltage-gated potassium channel Kv3.2Mitochondrial ATP-sensitive potassium channel
go.drugbank.com/bio_entities/BE0004923TargetHumansInward rectifier potassium channel that forms the pore of ATP-sensitive potassium channels (KATP), regulating potassium permeability as a function of cytoplasmic ATP and ADP concentrations in many different … Can form cardiac and smooth muscle-type KATP channels with ABCC9
Polypeptides: ATP-sensitive inward rectifier potassium channel 11, ATP-sensitive inward rectifier potassium channel 8Synonyms: Potassium channel, inwardly rectifying subfamily J member 11, Potassium channel, inwardly rectifying subfamily J member 8Inward rectifier potassium channel 4
go.drugbank.com/bio_entities/BE0005187TargetHumansCan be blocked by extracellular barium and cesium … Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.
Polypeptides: Inward rectifier potassium channel 4Synonyms: Potassium channel, inwardly rectifying subfamily J member 4Potassium-transporting ATPase subunit beta
go.drugbank.com/bio_entities/BE0000619TargetHumansPlays a structural and regulatory role in the assembly and membrane targeting of a functionally active pump (By similarity). … Interacts with the phosphorylation domain of the alpha subunit and functions as a ratchet, stabilizing the lumenal-open E2 conformation and preventing the reverse reaction of the transport cycle (By similarity
Polypeptides: Potassium-transporting ATPase subunit betaVoltage-gated potassium channel KCNC3
go.drugbank.com/bio_entities/BE0004725TargetHumansVoltage-gated potassium channel that plays an important role in the rapid repolarization of fast-firing brain neurons. … The channel opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical gradient.
Polypeptides: Voltage-gated potassium channel KCNC3Synonyms: Voltage-gated potassium channel subunit Kv3.3, Potassium voltage-gated channel subfamily C member 3pH-gated potassium channel KcsA
go.drugbank.com/bio_entities/BE0001355TargetStreptomyces lividansActs as a pH-gated potassium ion channel; changing the cytosolic pH from 7 to 4 opens the channel, although it is not clear if this is the physiological stimulus for channel opening.
Polypeptides: pH-gated potassium channel KcsAFunction: delayed rectifier potassium channel activityVoltage-gated potassium channel KCNC4
go.drugbank.com/bio_entities/BE0003319TargetHumansThe channel displays rapid activation and inactivation kinetics (PubMed:7993631) … Voltage-gated potassium channel that opens in response to the voltage difference across the membrane, forming a potassium-selective channel through which potassium ions pass in accordance with their electrochemical
Polypeptides: Voltage-gated potassium channel KCNC4Synonyms: Voltage-gated potassium channel subunit Kv3.4, Potassium voltage-gated channel subfamily C member 4Voltage-gated potassium channel KCNC1
go.drugbank.com/bio_entities/BE0004723TargetHumansVoltage-gated potassium channel that opens in response to the voltage difference across the membrane and through which potassium ions pass in accordance with their electrochemical gradient (PubMed:25401298 … Can form functional homotetrameric channels and heterotetrameric channels that contain variable proportions of KCNC2, and possibly other family members as well (By similarity).
Polypeptides: Voltage-gated potassium channel KCNC1Synonyms: Voltage-gated potassium channel subunit Kv4, Voltage-gated potassium channel subunit Kv3.1Inward rectifier potassium channel 2
go.drugbank.com/bio_entities/BE0009710TargetHumansProbably participates in establishing action potential waveform and excitability of neuronal and muscle tissues (PubMed:7590287, PubMed:7696590, PubMed:7840300) … Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it (PubMed:36149965, PubMed:7590287, PubMed:9490857).
Polypeptides: Inward rectifier potassium channel 2Synonyms: Cardiac inward rectifier potassium channel, Potassium channel, inwardly rectifying subfamily J member 2Inward rectifier potassium channel 2
go.drugbank.com/bio_entities/BE0027705TargetRatCan be blocked by extracellular barium and cesium. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues (By similarity). … Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it.
Polypeptides: Inward rectifier potassium channel 2Synonyms: Potassium channel, inwardly rectifying subfamily J member 2