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Displaying results 11 - 20 of 2873 in total
  1. Pathway

    Verapamil Calcium Channel Cardiac Muscle Relaxation Action Pathway

    smpdb.ca/view/SMP0126428
    Drug action

    This activity is dependent on calcium influx through L-type calcium channels. … Activation of L-type calcium channels allows the influx of calcium ions into the muscles upon depolarization and excitation of the channel.

    Drugs: Verapamil · Potassium cation · Calcium · Cyclic adenosine monophosphate
    Enzymes: Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-dependent T-type calcium channel subunit alpha-1G
  2. Pathway

    Enflurane Calcium Channel Cardiac Muscle Relaxation Action Pathway

    smpdb.ca/view/SMP0126668
    Drug action

    My decreasing the amount of intracellular calcium available, calcium cannot readily bind to calmodulin and muscle contraction is inhibited. … Studies have found that enflurane binds to the calcium channels in the cardiac sarcoplasmic reticulum causing cardio depressant effects.

    Drugs: ATP · Enflurane · Epinephrine · Calcium
    Enzymes: Sodium/calcium exchanger 1, Voltage-dependent T-type calcium channel subunit alpha-1G
  3. Indication

    Calcium Deficiency

    go.drugbank.com/conditions/DBCOND0052248
    Drugs: Calcium · Calcium Phosphate · Calcium carbonate · Calcium citrate · Calcium glubionate anhydrous · Calcium gluconate +4 more
    Synonyms: Calcium Deficiency, Calcium deficiency (disorder)
  4. Indication

    Calcium loss

    go.drugbank.com/conditions/DBCOND0098865
    Drugs: Calcium carbonate
    Synonyms: Calcium loss
  5. Indication

    Calcium Metabolism Disorders

    go.drugbank.com/conditions/DBCOND0047665
    Drugs: Calcium carbonate
    Synonyms: Calcium metabolism disorder, Calcium Metabolism Disorders
  6. Indication

    Calcium and Vitamin D Deficiencies

    go.drugbank.com/conditions/DBCOND0077928
    Drugs: Calcium Phosphate · Calcium carbonate · Cholecalciferol
    Synonyms: Calcium and Vitamin D Deficiencies
  7. Drug

    Sennosides

    go.drugbank.com/drugs/DB11365
    ApprovedInvestigational

    Sennosides (also known as senna glycoside or senna) is a medication used to treat constipation[FDA Label] and empty the large intestine before surgery. The medication is taken by mouth or via the rectum[FDA Label]. It typically begins wo...

    Mixtures: Senna/Docusate Sodium, Docusate SodiumProducts: Calcium Sennosides 20%, Calcium Sennosides 60%
  8. Drug

    Cholecalciferol

    go.drugbank.com/drugs/DB00169
    ApprovedInvestigationalNutraceutical

    Appropriate levels of vitamin D must be upheld in the body in order to maintain calcium and phosphorus levels in a healthy physiologic range to sustain a variety of metabolic functions, transcription regulation

    Synonyms: CalciolMixtures: Pure Calcium calcium, PNV Ferrous Fumarate Docusate Folic Acid
  9. Indication

    Chronic Hypocalcemia

    go.drugbank.com/conditions/DBCOND0134706
    Drugs: Calcium
  10. Pathway

    Bevantolol Beta Blocker Cardiac Action Pathway

    smpdb.ca/view/SMP0122915
    Drug action

    Bevantolol is a beta blocker and calcium channel blocker. It is an oral drug used for the treatment of angina pectoris and hypertension. … Protein kinase is required to activate calcium channels in the cell membrane, causing them to open and allow Ca2+ to enter the cell.

    Drugs: ATP · Bevantolol · Calcium
    Enzymes: Sodium/calcium exchanger 1, Voltage-dependent T-type calcium channel subunit alpha-1G