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Sodium-dependent dopamine transporter
go.drugbank.com/bio_entities/BE0000647TargetTransporterHumansAlso mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity).
Sulfotransferase 1A3
go.drugbank.com/bio_entities/BE0004767EnzymeHumansphospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, (R)-adrenaline/epinephrine, (R)-noradrenaline/norepinephrine
Alpha-1 adrenergic receptors
go.drugbank.com/bio_entities/BE0004863TargetHumansADRA1D binds the catecholamine ligands norepinephrine and epinephrine (PubMed:7815325, PubMed:8024574, PubMed:8183249) … ADRA1A binds the catecholamine ligands norepinephrine and epinephrine (PubMed:18802028, PubMed:37563160, PubMed:7815325, PubMed:8024574, PubMed:8183249, PubMed:8832064).
Beta adrenergic receptor
go.drugbank.com/bio_entities/BE0004872TargetHumansThe rank order of potency for physiological agonists is norepinephrine > epinephrine (PubMed:10188996, PubMed:2570461, PubMed:8641219). … ADRB2 binds epinephrine (Epi) with an approximately 30-fold greater affinity than norepinephrine (NE) (PubMed:2831218, PubMed:33093660, PubMed:7915137).
Dopamine receptor
go.drugbank.com/bio_entities/BE0009376TargetHumansIn addition to dopamine, also activated by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs (PubMed:16423344, PubMed:1840645, PubMed:27659709, PubMed:29051383, PubMed:9003072
Dopamine beta-hydroxylase
go.drugbank.com/bio_entities/BE0000138TargetEnzymeHumansCatalyzes the hydroxylation of dopamine to noradrenaline (also known as norepinephrine), and is thus vital for regulation of these neurotransmitters
Alpha-2C adrenergic receptor
go.drugbank.com/bio_entities/BE0000342TargetHumansThe rank order of potency for physiological agonists of ADRA2C is epinephrine > norepinephrine > dopamine (PubMed:2842764)
Dopamine receptor D4
go.drugbank.com/bio_entities/BE0000389TargetHumansIn addition to dopamine, also activated by epinephrine and norepinephrine, and by numerous synthetic agonists and drugs (PubMed:16423344, PubMed:1840645, PubMed:27659709, PubMed:29051383, PubMed:9003072
Alpha-1B adrenergic receptor
go.drugbank.com/bio_entities/BE0000575TargetHumansADRA1B binds the catecholamine ligands norepinephrine and epinephrine (PubMed:7815325, PubMed:8183249). Can also couple to G(14) and G(16) proteins (By similarity).
Beta-2 adrenergic receptor
go.drugbank.com/bio_entities/BE0000694TargetHumansADRB2 binds epinephrine (Epi) with an approximately 30-fold greater affinity than norepinephrine (NE) (PubMed:2831218, PubMed:33093660, PubMed:7915137).