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Displaying results 11 - 20 of 1841 in total
  1. Drug

    Glucosamine

    go.drugbank.com/drugs/DB01296
    Approved

    Osteoarthritis (OA) is a progressive and degenerative joint disease marked by loss of cartilage, bone changes, and synovial membrane inflammation. Treatment with chondroprotective drugs, such as glucosamine sulfate may offer additional b...

    Salts: Glucosamine sulfate potassium chloride, Glucosamine sulfate sodium chloride
  2. Drug

    Calcium magnesium potassium carbonate chloride hydroxide

    go.drugbank.com/drugs/DB14497
    Investigational

    Synonyms: Calcium magnesium potassium carbonate chloride hydroxide
  3. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    [L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide. … [L7423,L7426] Patients taking losartan should have their renal function and potassium levels monitored.[L7423] Losartan was granted FDA approval on 14 April 1995.[L7423]

    Salts: Losartan potassiumMixtures: Losartan Potassium HCTZ, Losartan Potassium and Hydrochlorothiazide
  4. Target

    Solute carrier family 12 member 6

    go.drugbank.com/bio_entities/BE0000140
    TargetTransporterHumans

    Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (PubMed:10600773, PubMed:11551954, PubMed:16048901, PubMed:18566107, PubMed:19665974, PubMed:21628467, PubMed:27485015

    Synonyms: Electroneutral potassium-chloride cotransporter 3Function: potassium
  5. Target

    Solute carrier family 12 member 7

    go.drugbank.com/bio_entities/BE0000276
    TargetTransporterHumans

    Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (PubMed:10913127).

    Synonyms: Electroneutral potassium-chloride cotransporter 4Function: potassium
  6. Target

    Solute carrier family 12 member 4

    go.drugbank.com/bio_entities/BE0000601
    TargetTransporterHumans

    Mediates electroneutral potassium-chloride cotransport when activated by cell swelling (PubMed:35759661). May contribute to cell volume homeostasis in single cells (PubMed:10913127, PubMed:34031912).

    Synonyms: Electroneutral potassium-chloride cotransporter 1
  7. Target

    Solute carrier family 12 member 5

    go.drugbank.com/bio_entities/BE0000047
    TargetTransporterHumans

    Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis (PubMed:12106695). … As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization

    Synonyms: Electroneutral potassium-chloride cotransporter 2
  8. Target

    Solute carrier family 12 member 5

    go.drugbank.com/bio_entities/BE0009674
    TransporterMouse

    Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis (By similarity). … As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization

    Synonyms: Electroneutral potassium-chloride cotransporter 2
  9. Target

    Solute carrier family 12 member 2

    go.drugbank.com/bio_entities/BE0000281
    TargetTransporterHumans

    Cation-chloride cotransporter which mediates the electroneutral transport of chloride, potassium and/or sodium ions across the membrane (PubMed:16669787, PubMed:32081947, PubMed:32294086, PubMed:33597714

    Synonyms: Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2
  10. Target

    Solute carrier family 12 member 1

    go.drugbank.com/bio_entities/BE0000502
    TargetTransporterHumans

    Renal sodium, potassium and chloride non-electrogenic ion symporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration

    Synonyms: Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1