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Etomidate Action Pathway
smpdb.ca/view/SMP0126127Drug actionEtomidate is a short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures. Imidazole derivative anesthetic and hypnotic with little effect o...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Eszopiclone Action Pathway
smpdb.ca/view/SMP0126150Drug actionEszopiclone is a sedative-hypnotic used in the treatment of insomnia, improving both the latency phase and the maintenance phase of sleep. Eszopiclone, marketed by Sepracor under the brand-name Lunesta, is a nonbenzodiazepine hypnotic dr...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Methylphenobarbital Action Pathway
smpdb.ca/view/SMP0126819Drug actionMephobarbital, a barbiturate, undergoes metabolism into phenobarbital and has been employed for similar purposes, particularly in managing epilepsy; however, there exists no evidence supporting its superiority over phenobarbital. It serv...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Methylphenobarbital · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Quinidine barbiturate Action Pathway
smpdb.ca/view/SMP0126833Drug actionThe administration of quinidine derivatives is utilized to monitor various skin and mucosal reactions. In certain cases, a papulopurpuric eruption can arise in patients (without thrombocytopenia) who are intermittently taking quinidine p...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Quinidine barbiturate · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Butobarbital Action Pathway
smpdb.ca/view/SMP0126835Drug actionButobarbital, also known as butethal or butobarbitone, functions as both a sedative and a hypnotic drug, primarily intended for treating insomnia. Belonging to the barbiturate group of medicines, it is presumed to act on GABA receptors i...
Drugs: Pyridoxal phosphate · Glutamic acid · ATP · Butobarbital · Calcium · Magnesium cation +3 moreEnzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2Triamterene
go.drugbank.com/drugs/DB00384ApprovedTriamterene is a weak antagonist of folic acid, and a photosensitizing drug.[L6163] Triamterene was approved by the Food and Drug Administration in the U.S. in 1964.
Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)
smpdb.ca/view/SMP0000543DiseaseMethylenetetrahydrofolate reductase deficiency (MTHFRD; Homocystinuria due to defect of n(5,10)-methylene THF deficiency) is caused by a defect in the MTHFR gene which codes for methylenetetrahydrofolate reductase. Methylenetetrahydrofol...
Argininosuccinic Aciduria
smpdb.ca/view/SMP0125766DiseaseIt results in accumulation of citrulline, arginosuccinic acid, L-arginine, and L-glutamic acid in plasma as well as ammonia in blood. Infants are lethargic and unwilling to eat. … Argininosuccinic Aciduria, (Argininosuccinase Deficiency, Argininosuccinate Lyase Deficiency, ASL Deficiency) is an autosomal recessive disorder caused by a mutation in the ASL gene which codes for argininosuccinate
Drugs: Pyridoxal phosphate · Pyruvic acid · Arginine · Aspartic acid · Ornithine · L-Glutamine +11 moreEnzymes: Y+L amino acid transporter 1, Neutral amino acid transporter AMagnesium trisilicate
go.drugbank.com/drugs/DB09281ApprovedMagnesium trisilicate is an inorganic compound that is used as an antacid in the treatment of peptic ulcers.
Mixtures: Mag-A-folic Tab, R90 Anti-acide TabCategories: Gastric Acid Lowering AgentsGlutethimide Action Pathway
smpdb.ca/view/SMP0126131Drug actionGlutethimide is a hypnotic and sedative. Its use has been largely superseded by other drugs. It can be found under the brand name Doriden and is used to treat insomnia. The hypnotic effect is roughly analogous to that of pentobarbital. I...
Enzymes: Vesicular inhibitory amino acid transporter, Gamma-aminobutyric acid type B receptor subunit 2