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Displaying results 191 - 200 of 8412 in total
  1. Drug

    Antihemophilic factor (recombinant), PEGylated

    go.drugbank.com/drugs/DB09329
    ApprovedInvestigational

    PEGylation decreases factor VIII clearance and allowing for an increased duration of drug circulation in the plasma [L1529].

    Products: ADYNOVATE 500®IU / VIAL, ADYNOVATE®250IU/VIAL
  2. Drug

    Doripenem

    go.drugbank.com/drugs/DB06211
    ApprovedWithdrawn

    In a clinical trial of doripenem treatment in ventilator associated pneumonia (vs. imipenem and cilastatin), it was found that doripenem carried an increased risk of death and lower clinical cure rates

    Products: DORIBAX® VIAL, REDIDOR 500 MG /VIAL
  3. Drug

    Cefazolin

    go.drugbank.com/drugs/DB01327
    ApprovedInvestigational

    A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.

    Products: CEFAZOLIN SANDOZ 1 g/vial, CEFAZOLIN SANDOZ 1G VIAL
  4. Drug

    Factor IX Complex (Human)

    go.drugbank.com/drugs/DB11330
    ApprovedInvestigational

    Factor IX Complex is a sterile, lyophilized concentrate composed of a number of Vitamin K-dependent clotting factors found in functioning human plasma. Also known as prothrombin complex concentrate, products containing this complex often...

    Mixtures: Bebulin Vh Inj 1000unit/vialProducts: Bebulin Vh 500unit/vial, Alphanine Pws Inj 1500unit/vial
  5. Drug

    Botulinum toxin type A

    go.drugbank.com/drugs/DB00083
    ApprovedInvestigational

    In 2002, botulinum toxin A, also known as onabotulinumtoxinA or Botox, was the first type A botulism toxin to be introduced into the market for cosmetic use. With a wide variety of applications and favourable safety profile, Botulinum to...

    Products: Powder for Solution for Injection 50 Units/Vial, Powder for Solution for Injection 200 Units/Vial
  6. Drug

    Cyclophosphamide

    go.drugbank.com/drugs/DB00531
    ApprovedInvestigational

    Precursor of an alkylating nitrogen mustard antineoplastic and immunosuppressive agent that must be activated in the liver to form the active aldophosphamide.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 InducersProducts: Procytox Vial 200mg, Procytox Vial 1000mg
  7. Drug

    Benzylpenicillin

    go.drugbank.com/drugs/DB01053
    ApprovedInvestigationalVet approved

    Resistance patterns, susceptibility and treatment guidelines vary across regions. … It is a natural penicillin antibiotic that is administered intravenously or intramuscularly due to poor oral absorption.

    Mixtures: Bicillin A-P Injection Pws, Bicillin A-P Injection PwsSynonyms: PG
  8. Drug

    Progesterone

    go.drugbank.com/drugs/DB00396
    ApprovedInvestigationalVet approved

    A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609].

    Mixtures: Estradiol and ProgesteroneCategories: P-glycoprotein inducers, P-glycoprotein inhibitors
  9. Drug

    Brompheniramine

    go.drugbank.com/drugs/DB00835
    Approved

    Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.

    Mixtures: J-tan D Pd, Mar-cof BPCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2B6 Substrates
  10. Drug

    Fluoride ion

    go.drugbank.com/drugs/DB11257
    ApprovedInvestigational

    It also plays an essential physiological role, such as enhancing the resistance profile and strength of the surface tooth enamel.

    Mixtures: ZYMAFLUOR D 500, ZYMAFLUOR D 500Products: Topex Neutral pH Fluoride Gel Mint, Topex Neutral pH Fluoride Gel Strawberry