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Ferumoxytol
go.drugbank.com/drugs/DB06215ApprovedInvestigationalFerumoxytol is an intravenously administered iron preparation previously indicated in the EU and the US for the treatment of iron deficiency anemia in adult patients with chronic kidney disease (CKD) [ … [L54506] It is comprised of superparamagnetic iron oxide nanoparticles which are coated by a semi-synthetic carbohydrate shell in an isotonic, neutral pH solution that may be administered at relatively
Bendroflumethiazide
go.drugbank.com/drugs/DB00436ApprovedInvestigational(From Martindale, The Extra Pharmacopoeia, 30th ed, p810) … A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders.
Mixtures: Nadolol and Bendroflumethiazide, Nadolol and BendroflumethiazideCategories: bendroflumethiazide and potassium, Genito Urinary System and Sex HormonesAcylcarnitine (2Z)-2-(propan-2-yl)but-2-enedioylcarnitine
smpdb.ca/view/SMP0123554Metabolic-2-enedioylcarnitine from forming and thereby preventing it from being transported into the mitochondria. … The general role of acylcarnitines is to transport acyl-groups, organic acids and fatty acids, from the cytoplasm into the mitochondria so that they can be broken down to produce energy.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreAcetarsol
go.drugbank.com/drugs/DB13268ApprovedWithdrawnIt has been canceled and withdrawn from the market since August 12, 1997.[L1113] … [L2622] It was first discovered in 1921 by Ernest Fourneau at the Pasteur Institute. It was developed by Neolab Inc, and approved by Health Canada as an antifungal on December 31, 1964.
Categories: Alimentary Tract and Metabolism, Genito Urinary System and Sex HormonesGadobenic acid
go.drugbank.com/drugs/DB00743ApprovedInvestigational[A263166] As gadobenate dimeglumine is specifically taken up by hepatocytes and excreted through the biliary system, it is a useful contrast agent for liver MRI. … [A263086] It differs from other GBCAs due to the benzene ring that confers weak protein binding, thus leading to an increased R1 and R2 relaxivity.
Adiponectin receptor
go.drugbank.com/bio_entities/BE0010287TargetHumansRequired for normal glucose and fat homeostasis and for maintaining a normal body weight. … Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism (PubMed:12802337, PubMed:25855295). Required for normal body fat and glucose homeostasis.
Synonyms: Progestin and adipoQ receptor family member 1, Progestin and adipoQ receptor family member IMoexipril
go.drugbank.com/drugs/DB00691ApprovedInvestigationalIt works by relaxing blood vessels, causing them to widen. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.
Mixtures: FEMPRESS PLUS 15MG/25MG, Moexipril Hydrochloride and HydrochlorothiazideCategories: ACE Inhibitors and Diuretics, moexipril and diureticsAntipyrine
go.drugbank.com/drugs/DB01435ApprovedAn analgesic and antipyretic that has been given by mouth and as ear drops. Antipyrine is often used in testing the effects of other drugs or diseases on drug-metabolizing enzymes in the liver. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p29)
Mixtures: Antipyrine and Benzocaine, Antipyrine and BenzocaineCategories: Analgesics and AnestheticsOpioid Dependence
go.drugbank.com/conditions/DBCOND0030983Synonyms: [X]Mental and behavioral disorders due to use of opioids: dependence syndrome, [X]Mental and behavioural disorders due to use of opioids: dependence syndromePegaptanib
go.drugbank.com/drugs/DB04895ApprovedWithdrawnPegatinib aids neovascular age-related macular degeneration by binding to VEGF which in order reduces angiogenesis and vessel permeability. Pegaptanib was granted FDA approval on 17 September 2004.
Categories: Nucleic Acids, Nucleotides, and Nucleosides