Search
Immune Thrombocytopenia (ITP)
go.drugbank.com/conditions/DBCOND0035132Drugs: Azathioprine · Cortisone acetate · Cyclosporine · Dexamethasone · Hydrocortisone · Hydrocortisone succinate +6 moreSynonyms: Thrombocytopenia in Subjects With Immune (Idiopathic) Thrombocytopenic Purpura (ITP)Ferrous fumarate
go.drugbank.com/drugs/DB14491ApprovedInvestigationalUsed in treatment of iron deficiency anemia.
Synonyms: Iron(2+) fumarateMixtures: Vc II, Iron IIPeginesatide
go.drugbank.com/drugs/DB08894ApprovedWithdrawnPeginesatide consists of two 21-amino acid chains that are covalently bonded by a linker derived from iminodiacetic acid and β-alanine. FDA approved March 27, 2012. … Chemically, peginesatide is designed to mimic the pharmacological activity of erythropoietin, but is not a replica of the structure itself.
Categories: Compounds used in a research, industrial, or household settingGadoteridol
go.drugbank.com/drugs/DB00597ApprovedInvestigational[A263076,A263081,L49871] It was 1 of the 3 macrocyclic gadolinium-based contrast agents (GBCAs) that was mandated by the EMA to replace linear gadolinium-based contrast agents due to concerns about retained … [A263076] Initially approved by the FDA in 1992, gadoteridol received additional approval in 2020 for use in pediatric patients less than 2 years old.[L49876]
Synonyms: GD-HP-DO 3A, gadolinium 2,2',2''-[10-(2-hydroxypropyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl]triacetateCategories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of ChemicalsPindolol
go.drugbank.com/drugs/DB00960ApprovedInvestigationalPindolol is a first generation non-selective beta blocker used in the treatment of hypertension. … [A231059] Research into pindolol's use in the treatment of hypertension began in the early 1970s.[A231064] Pindolol was granted FDA approval on 3 September 1982.[L32348]
Synonyms: 1-(1H-indol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1-(1H-indol-4-yloxy)-3-(propan-2-ylamino)-propan-2-olInternational brands: Blockin L, Blocklin LToripalimab
go.drugbank.com/drugs/DB15043ApprovedInvestigationalIt was first approved in China in December 2018 for the treatment of unresectable or metastatic melanoma in previously treated patients. … The proliferation of some cancers can be attributed, at least in part, to the suppression of host tumor surveillance.
Categories: PD-1/PD-L1 (Programmed cell death protein 1/death ligand 1) inhibitors, Programmed Death Receptor-1 Blocking AntibodyTrifluoperazine
go.drugbank.com/drugs/DB00831ApprovedA phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic.
Synonyms: 10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoromethyl)-10H-phenothiazine, trifluoromethyl-10-(3'-(1-methyl-4-piperazinyl)propyl)phenothiazineMixtures: CUAIT - D COMPRIMIDOS., Stelabid No 2Protein S100-A12
go.drugbank.com/bio_entities/BE0001206TargetHumansS100A12 is a calcium-, zinc- and copper-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response.
Synonyms: Calcium-binding protein in amniotic fluid 1Riociguat
go.drugbank.com/drugs/DB08931ApprovedInvestigationalRiociguat is a soluble guanylate cyclase (sGC) agonist approved in the USA, Europe and several other regions for patients with group I PAH (pulmonary arterial hypertension) in WHO FC II or III; and for … the treatment of patients with inoperable CTEPH (chronic thromboembolic pulmonary hypertension), or persistent/recurrent PH (pulmonary hypertension) after pulmonary endarterectomy in WHO FC II or III.
Synonyms: Methyl N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methyl-carbaminateCategories: P-glycoprotein substrates, Cytochrome P-450 Substrates