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Sodium-dependent phosphate transporter 2
go.drugbank.com/bio_entities/BE0008680TransporterHumansSodium-phosphate symporter which preferentially transports the monovalent form of phosphate with a stoichiometry of two sodium ions per phosphate ion (PubMed:12205090, PubMed:15955065, PubMed:16790504, PubMed:17494632, PubMed:22327515, P...
Synonyms: Gibbon ape leukemia virus receptor 2Function: signaling receptor activityC-type lectin domain family 10 member A
go.drugbank.com/bio_entities/BE0016623TargetHumansActs as a signaling receptor at the interface of APC-T cell interactions. … Acts as an endocytic pattern recognition receptor involved in antitumor immunity.
Synonyms: DC-asialoglycoprotein receptorTopiroxostat
go.drugbank.com/drugs/DB01685InvestigationalTopiroxostat is a selective xanthine oxidase inhibitor developed for treatment and management of hyperuricemia and gout. Xanthine oxidase, or xanthine oxidoreductase (XOR), regulates purine metabolism, and inhibition of the enzyme result...
Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C8 InhibitorsAmlodipine
go.drugbank.com/drugs/DB00381ApprovedInvestigationalAmlodipine, initially approved by the FDA in 1987, is a popular antihypertensive drug belonging to the group of drugs called dihydropyridine calcium channel blockers. Due to their selectivity for the peripheral blood vessels, dihydropyri...
Mixtures: RAMIPRIL HEXAL PL AM 5/5, RAMIPRIL HEXAL PL AM 5/5Categories: Angiotensin II receptor blockers (ARBs) and calcium channel blockers, P-glycoprotein inhibitorsMitochondrial potassium channel ATP-binding subunit
go.drugbank.com/bio_entities/BE0003673TransporterHumansATP-binding subunit of the mitochondrial ATP-gated potassium channel (mitoK(ATP)) (PubMed:31435016). Together with pore-forming subunit CCDC51/MITOK of the mitoK(ATP) channel, mediates ATP-dependent potassium currents across the mitochon...
Synonyms: Mitochondrial sulfonylurea-receptorTumor necrosis factor ligand superfamily member 11
go.drugbank.com/bio_entities/BE0003517TargetHumansCytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions ...
Synonyms: Receptor activator of nuclear factor kappa-B ligandHepatocyte nuclear factor 4-alpha
go.drugbank.com/bio_entities/BE0004019TargetHumansTranscriptional regulator which controls the expression of hepatic genes during the transition of endodermal cells to hepatic progenitor cells, facilitating the recruitment of RNA pol II to the promoters of target genes (PubMed:30597922)...
Synonyms: Nuclear receptor subfamily 2 group A member 1Drometrizole trisiloxane
go.drugbank.com/drugs/DB11585ApprovedDrometrizole trisiloxane is a photostable UVA and UVB light filter . The compound is a lipophilic benzotriazole derivative marketed as Meroxyl XL by L'Oreal, although sunscreens with drometrizole trisiloxane are currently only approved f...
Mixtures: Kiehls Since 1851 Dermatologist Solutions Ultra Light Daily UV Defense Tone Up SPF 50 PA Plus Plus Plus Plus AntipollutionHomeodomain-interacting protein kinase 3
go.drugbank.com/bio_entities/BE0009448TargetHumansEnhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors.
Synonyms: Androgen receptor-interacting nuclear protein kinaseBarnidipine
go.drugbank.com/drugs/DB09227InvestigationalBarnidipine is a long-acting novel calcium antagonist that belongs to the dihydropyridine (DHP) group of calcium channel blockers. Used in the treatment of hypertension, barnidipine displays high affinity for the calcium channels of the ...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inhibitors