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Kinesin-like protein KIF11
go.drugbank.com/bio_entities/BE0001852TargetHumansMotor protein required for establishing a bipolar spindle and thus contributing to chromosome congression during mitosis (PubMed:19001501, PubMed:37728657). Required in non-mitotic cells for transport of secretory proteins from the Golgi...
Synonyms: Thyroid receptor-interacting protein 5Cannabidivarin
go.drugbank.com/drugs/DB14050InvestigationalIt is one of over 100 cannabinoids identified from the Cannabis plant that can modulate the physiological activity of cannabis, or marijuana [A32584]. … The anti-epileptic activity of CBD and CBDV is thought to be modulated by their effects on transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as the capsaicin receptor
L-selectin
go.drugbank.com/bio_entities/BE0010361TargetHumansCalcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells (PubMed:12403782, PubMed:28011641, PubMed:28489325). Mediates the adherence of lymphocytes to endothelial cells of high endothelial ven...
Synonyms: Lymph node homing receptorCalcium-activated potassium channel subunit beta-4
go.drugbank.com/bio_entities/BE0004424TargetHumansRegulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium se...
Synonyms: Charybdotoxin receptor subunit beta-4Calcium-activated potassium channel subunit beta-2
go.drugbank.com/bio_entities/BE0003196TargetHumansRegulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Acts as a negative regulator that confers ra...
Synonyms: Charybdotoxin receptor subunit beta-2E3 ubiquitin-protein ligase XIAP
go.drugbank.com/bio_entities/BE0001156TargetHumansMulti-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis...
Synonyms: Baculoviral IAP repeat-containing protein 4Potassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnA white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives. The FDA withdrew its approval for the use of all solid oral dosage form dr...
Mixtures: PISA, SOLUCION HT PISAProtein-tyrosine kinase 2-beta
go.drugbank.com/bio_entities/BE0000871TargetHumansNon-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. … Promotes phosphorylation of NMDA receptors by SRC family members, and thereby contributes to the regulation of NMDA receptor ion channel activity and intracellular Ca(2+) levels.
Synonyms: Calcium-regulated non-receptor proline-rich tyrosine kinaseTIR domain-containing adapter molecule 1
go.drugbank.com/bio_entities/BE0016552TargetHumansInvolved in innate immunity against invading pathogens. Adapter used by TLR3, TLR4 (through TICAM2) and TLR5 to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis (PubMed:12471095, PubMed:125390...
Synonyms: Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon betaCalcium-activated potassium channel
go.drugbank.com/bio_entities/BE0004906TargetHumansPossibly induces sleep when activated by melatonin and through melatonin receptor MTNR1A-dependent dissociation of G-beta and G-gamma subunits, leading to increased sensitivity to Ca(2+) and reduced synaptic
Synonyms: Charybdotoxin receptor subunit beta-1, Charybdotoxin receptor subunit beta-2