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Displaying results 221 - 230 of 302 in total
  1. Target

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3

    go.drugbank.com/bio_entities/BE0000684
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-B9
  2. Target

    Dihydrolipoyl dehydrogenase

    go.drugbank.com/bio_entities/BE0002986
    TargetPseudomonas fluorescens

    The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2).

    Synonyms: E3 component of 2-oxoglutarate dehydrogenase complex
  3. Indication

    Temporomandibular Joint Dysfunction

    go.drugbank.com/conditions/DBCOND0039544
    Drugs: Botulinum toxin type A
    Synonyms: Costen's complex
  4. Target

    Tubulin gamma-1 chain

    go.drugbank.com/bio_entities/BE0003713
    TargetHumans

    Gamma-tubulin is a key component of the gamma-tubulin ring complex (gTuRC) which mediates microtubule nucleation (PubMed:38305685, PubMed:38609661, PubMed:39321809).

    Synonyms: Gamma-tubulin complex component 1
  5. Target

    Cartilage oligomeric matrix protein

    go.drugbank.com/bio_entities/BE0000899
    TargetHumans

    Plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix...

    Synonyms: COMP
  6. Target

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

    go.drugbank.com/bio_entities/BE0000081
    TargetHumans

    Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. … Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

    Synonyms: Complex I-42kD
  7. Target

    Calnexin

    go.drugbank.com/bio_entities/BE0001011
    TargetHumans

    Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation.

    Synonyms: Major histocompatibility complex class I antigen-binding protein p88
  8. Target

    NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

    go.drugbank.com/bio_entities/BE0000305
    TargetHumans

    Required for proper complex I assembly (PubMed:28671271). Complex I functions in the transfer of electrons from NADH to the respiratory chain. … Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis.

    Synonyms: Complex I-39kD
  9. Target

    Nuclear factor of activated T-cells, cytoplasmic 1

    go.drugbank.com/bio_entities/BE0004878
    TargetHumans

    Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation a...

    Synonyms: NFAT transcription complex cytosolic component
  10. Target

    NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

    go.drugbank.com/bio_entities/BE0000191
    TargetEnzymeHumans

    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor … Essential for the catalytic activity and assembly of complex I (PubMed:14729820, PubMed:24028823, PubMed:30140060)

    Synonyms: Complex I-30kD