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Displaying results 221 - 230 of 536 in total
  1. Target

    Holliday junction branch migration complex subunit RuvB

    go.drugbank.com/bio_entities/BE0001514
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    The RuvA-RuvB-RuvC complex processes Holliday junction (HJ) DNA during genetic recombination and DNA repair, while the RuvA-RuvB complex plays an important role in the rescue of blocked DNA replication … The RuvB hexamer acts as an ATP-dependent pump, pulling dsDNA into and through the RuvAB complex.

    Polypeptides: Holliday junction branch migration complex subunit RuvB
  2. Target

    Cytochrome b6-f complex iron-sulfur subunit

    go.drugbank.com/bio_entities/BE0002474
    TargetMastigocladus laminosus

    Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions.

    Polypeptides: Cytochrome b6-f complex iron-sulfur subunit
  3. Target

    Cytochrome b-c1 complex subunit Rieske, mitochondrial

    go.drugbank.com/bio_entities/BE0003858
    TargetHumans

    The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase … The Rieske protein is a catalytic core subunit containing a [2Fe-2S] iron-sulfur cluster.

    Polypeptides: Cytochrome b-c1 complex subunit Rieske, mitochondrialSynonyms: Complex III subunit 5, Cytochrome b-c1 complex subunit 5
  4. Target

    Major histocompatibility complex class I-related protein 1

    go.drugbank.com/bio_entities/BE0003573
    TargetHumans

    In complex with B2M preferentially presents riboflavin-derived metabolites to semi-invariant TRAV1.2 TCRs on MAIT cells, guiding immune surveillance of the microbial metabolome at mucosal epithelial barriers

    Polypeptides: Major histocompatibility complex class I-related protein 1
  5. Target

    ATP synthase F(1) complex subunit gamma, mitochondrial

    go.drugbank.com/bio_entities/BE0003842
    TargetHumans

    ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Subunit gamma, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated

    Polypeptides: ATP synthase F(1) complex subunit gamma, mitochondrial
  6. Target

    ATP synthase F(0) complex subunit e, mitochondrial

    go.drugbank.com/bio_entities/BE0009021
    TargetHumans

    Part of the complex F(0) domain (PubMed:37244256) … ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256).

    Polypeptides: ATP synthase F(0) complex subunit e, mitochondrialFunction: protein-containing complex binding
  7. Drug

    Betamethasone phosphate

    go.drugbank.com/drugs/DB14669
    ApprovedVet approved

    [L11994] Betamethasone sodium phosphate was granted FDA approval on 3 March 1965.[L11994]

  8. Drug

    Methylphenidate

    go.drugbank.com/drugs/DB00422
    ApprovedInvestigational

    Methylphenidate contains a blackbox warning stating that CNS stimulants, including methylphenidate-containing products and amphetamines, have a high potential for abuse and dependence. … areas is associated with the reinforcing and addictive properties of psychostimulants such as methylphenidate, and even amplifies the potency and reinforcing effects of other drugs of abuse such as amphetamines

  9. Target

    ATP synthase F(1) complex subunit beta, mitochondrial

    go.drugbank.com/bio_entities/BE0003841
    TargetEnzymeHumans

    ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel (PubMed:37244256). … Catalytic subunit beta, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which

    Polypeptides: ATP synthase F(1) complex subunit beta, mitochondrial
  10. Target

    Actin-related protein 2/3 complex subunit 2

    go.drugbank.com/bio_entities/BE0004252
    TargetHumans

    Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF) (PubMed:9230079). … The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility (PubMed:9230079).

    Polypeptides: Actin-related protein 2/3 complex subunit 2Synonyms: Arp2/3 complex 34 kDa subunit