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Displaying results 2641 - 2650 of 10000 in total
  1. Drug

    Olsalazine

    go.drugbank.com/drugs/DB01250
    Approved

    [A257078] Olsalazine is an anti-inflammatory agent that works by inhibiting cyclooxygenase and lipoxygenase, subsequently reducing the production of pro-inflammatory factors like prostaglandin and leukotriene … [A257078] Olsalazine comprises two mesalamine molecules joined by an azo bridge, which is cleaved in the colon.

    Categories: Alimentary Tract and Metabolism
  2. Drug

    Lutein

    go.drugbank.com/drugs/DB00137
    ApprovedNutraceutical

    Lutein is synthesized only by plants and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrots. … In green plants, xanthophylls act to modulate light energy and serve as non-photochemical quenching agents to deal with triplet chlorophyll (an excited form of chlorophyll), which is overproduced at very

  3. Indication

    Conjunctivitis caused by Chlamydia

    go.drugbank.com/conditions/DBCOND0021916
    Drugs: Demeclocycline
    Synonyms: (Viral and chlamydial disease NOS) or (catscratch fever) or (conjunctivitis: [chlamydia] or [trachoma])
  4. Indication

    Seasonal Allergies

    go.drugbank.com/conditions/DBCOND0038236
    Drugs: Fluticasone furoate · Mometasone furoate · Phenylephrine · Pseudoephedrine
    Synonyms: Vasomotor and allergic rhinitis
  5. Drug

    Selenomethionine

    go.drugbank.com/drugs/DB11142
    ApprovedInvestigational

    Selenomethionine is a naturally occuring amino acid in some plant materials such as cereal grains, soybeans and enriched yeast but it cannot be synthesized from animals or humans. … It can be produced from post-structural modifications.

    Categories: Amino Acids, Peptides, and Proteins
  6. Drug

    Isoeugenol

    go.drugbank.com/drugs/DB14188
    Approved

    It is also a significant dermatologic sensitizer and allergen, and as a result has been restricted to 200 p.p.m. since 1998 according to guidelines issued by the fragrance industry [A34278]. … Isoeugenol is a commonly used fragrance added to many commercially available products, and occurs naturally in the essential oils of plants such as ylang-ylang.

  7. Drug

    Fecal microbiota

    go.drugbank.com/drugs/DB17743
    ApprovedInvestigational

    [A259172] REBYOTA, a live fecal microbiota suspension for rectal use, was approved by the FDA in November 2022. … Recurrent CDI has a high risk of mortality and a high failure rate.

  8. Drug

    Palovarotene

    go.drugbank.com/drugs/DB05467
    Approved

    [L39990,L40020] It has been granted rare pediatric disease and breakthrough therapy designations from the US FDA, although a previously submitted NDA was withdrawn in August 2021 pending the resubmission … [A244920] The ossification occurring as a result of FOP is insidious and cumulative and is provoked during flare-ups or in response to injury.

  9. Drug

    Phenindione

    go.drugbank.com/drugs/DB00498
    ApprovedInvestigational

    An indandione that has been used as an anticoagulant. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higher incidence of severe adverse effects. … (From Martindale, The Extra Pharmacopoeia, 30th ed, p234)

    Categories: Blood and Blood Forming Organs, Vitamin K Antagonists
  10. Target

    Retinol dehydrogenase 12

    go.drugbank.com/bio_entities/BE0000726
    TargetHumans

    May play an important function in photoreceptor cells to detoxify 4-hydroxynonenal and potentially other toxic aldehyde products resulting from lipid peroxidation (PubMed:19686838). … Displays high activity towards 9-cis, 11-cis and all-trans-retinal. Shows very weak activity towards 13-cis-retinol (PubMed:12226107, PubMed:15865448).

    Synonyms: All-trans and 9-cis retinol dehydrogenase