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Displaying results 2661 - 2670 of 10000 in total
  1. Indication

    Metastatic Malignant Neoplasm to the Leptomeninges

    go.drugbank.com/conditions/DBCOND0057483
    Drugs: Cytarabine
    Synonyms: Metastatic Malignant Neoplasm in the Leptomeninges
  2. Target

    CAI-1 autoinducer synthase

    go.drugbank.com/bio_entities/BE0004287
    TargetVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

    Required for the synthesis of the quorum-sensing autoinducer CAI-1 ((S)-3-hydroxytridecan-4-one) which probably functions as an intragenus signal.

    Polypeptides: CAI-1 autoinducer synthase
  3. Indication

    Opioid Dependence

    go.drugbank.com/conditions/DBCOND0030983
    Drugs: Buprenorphine · Lactose · Levomethadone · Naloxone · Naltrexone
    Synonyms: [X]Mental and behavioral disorders due to use of opioids: dependence syndrome, [X]Mental and behavioural disorders due to use of opioids: dependence syndrome
  4. Drug

    Triethylhexanoin

    go.drugbank.com/drugs/DB14102
    Investigational

    Triethylhexanoin is an ingredient of cosmetic products as a fragrant solvent.

    Categories: Compounds used in a research, industrial, or household settingProducts: 3ce Lip Color 906 Bite It
  5. Drug

    Chlorobutanol

    go.drugbank.com/drugs/DB11386
    ApprovedVet approvedWithdrawn

    Similar in nature to chloral hydrate, it is formed by the simple nucleophilic addition of chloroform and acetone. … Chlorobutanol, or chlorbutol, is an alcohol-based preservative with no surfactant activity [A32746].

    Mixtures: NOSTIL 75 MG/60MG/35MG BURUN SPREYİ, ÇÖZELTİ, 15 MLCategories: Compounds used in a research, industrial, or household setting, Antiemetics and Antinauseants
  6. Drug

    Piperonyl butoxide

    go.drugbank.com/drugs/DB09350
    ApprovedVet approved

    It has no pesticidal activity of its own, but acts to increase the activity of pesticides such as carbamates, pyrethrins, pyrethroids, and rotenone. … Piperonyl butoxide (PBO) is an organic compound used as a component of pesticide formulations. It is used for the treatment of head, pubic (crab), and body lice. Piperonyl butoxide is a synergist.

    Mixtures: Up and up lice killing maximum strength, Medi and Lice Lice KillingCategories: Compounds used in a research, industrial, or household setting
  7. Drug

    Gliclazide

    go.drugbank.com/drugs/DB01120
    ApprovedInvestigational

    Gliclazide is extensively metabolized by the liver; its metabolites are excreted in both urine (60-70%) and feces (10-20%). … Gliclazide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).

    Categories: Drugs Used in Diabetes, Alimentary Tract and MetabolismProducts: Gliavis IR Tablet 80mg, Rolazide Tablet 80mg
  8. Indication

    Osteolytic lesion

    go.drugbank.com/conditions/DBCOND0020866
    Drugs: Pamidronic acid
    Synonyms: (Other and unspecified bone or cartilage disorders) or (osteolytic lesion)
  9. Indication

    Cutaneous lesions

    go.drugbank.com/conditions/DBCOND0021486
    Drugs: Alitretinoin · Lidocaine
    Synonyms: (Other skin and subcut tissue disease NOS) or (skin lesion)
  10. Drug

    Enasidenib

    go.drugbank.com/drugs/DB13874
    ApprovedInvestigational

    First developed by Agios Pharmaceuticals and licensed to Celgene, enasidenib was approved by U.S. Food and Drug Administration on August 1, 2017. … This small molecule acts as an allosteric inhibitor of mutant IDH2 enzyme to prevent cell growth, and it also has shown to block several other enzymes that play a role in abnormal cell differentiation.

    Categories: Antineoplastic and Immunomodulating Agents