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Displaying results 261 - 270 of 2828 in total
  1. Target

    Probable monocarboxylate transporter 5

    go.drugbank.com/bio_entities/BE0000195
    TargetHumans

    Probable monocarboxylate transporter

    Polypeptides: Probable monocarboxylate transporter 5Synonyms: Monocarboxylate transporter 4
  2. Target

    Mitochondrial ornithine transporter 1

    go.drugbank.com/bio_entities/BE0000201
    TargetHumans

    Lysine and arginine are also transported by the antiport mechanism (Probable) (PubMed:12807890). … Catalyzes the exchange between cytosolic ornithine and mitochondrial citrulline plus an H(+), the proton compensates the positive charge of ornithine thus leading to an electroneutral transport.

    Polypeptides: Mitochondrial ornithine transporter 1
  3. Target

    Sodium-dependent noradrenaline transporter

    go.drugbank.com/bio_entities/BE0000486
    TargetTransporterHumans

    Can also mediate sodium- and chloride-dependent transport of dopamine (PubMed:11093780, PubMed:8125921, PubMed:39395208, PubMed:39048818) … Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline), the primary signaling neurotransmitter in the autonomic sympathetic nervous system (PubMed:2008212, PubMed

    Polypeptides: Sodium-dependent noradrenaline transporterSynonyms: Norepinephrine transporter
  4. Target

    Sodium-dependent dopamine transporter

    go.drugbank.com/bio_entities/BE0000647
    TargetTransporterHumans

    Also mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (By similarity). … Mediates sodium- and chloride-dependent transport of dopamine (PubMed:10375632, PubMed:11093780, PubMed:1406597, PubMed:15505207, PubMed:19478460, PubMed:39112701, PubMed:39112703, PubMed:39112705, PubMed

    Polypeptides: Sodium-dependent dopamine transporterSynonyms: DA transporter
  5. Target

    Sodium-dependent serotonin transporter

    go.drugbank.com/bio_entities/BE0000749
    TargetTransporterHumans

    Serotonin transporter that cotransports serotonin with one Na(+) ion in exchange for one K(+) ion and possibly one proton in an overall electroneutral transport cycle. … Mechanistically, the transport cycle starts with an outward-open conformation having Na1(+) and Cl(-) sites occupied.

    Polypeptides: Sodium-dependent serotonin transporterSynonyms: 5HT transporter
  6. Target

    Proton-coupled folate transporter

    go.drugbank.com/bio_entities/BE0001048
    TransporterTargetHumans

    Protonation of residues in the outward open state primes the protein for transport (PubMed:34040256). … Involved in the intestinal absorption of folates at the brush-border membrane of the proximal jejunum, and the transport from blood to cerebrospinal fluid across the choroid plexus (PubMed:17129779, PubMed

    Polypeptides: Proton-coupled folate transporterFunction: folic acid transmembrane transporter activity
  7. Target

    Vitamin B12 transporter BtuB

    go.drugbank.com/bio_entities/BE0001470
    TargetTransporterEscherichia coli (strain K12)

    It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB.

    Polypeptides: Vitamin B12 transporter BtuBFunction: ABC-type vitamin B12 transporter activity
  8. Target

    Antigen peptide transporter 1

    go.drugbank.com/bio_entities/BE0003109
    TransporterHumans

    ABC transporter associated with antigen processing. … In complex with TAP2 mediates unidirectional translocation of peptide antigens from cytosol to endoplasmic reticulum (ER) for loading onto MHC class I (MHCI) molecules (PubMed:25377891, PubMed:25656091

    Polypeptides: Antigen peptide transporter 1Synonyms: Peptide transporter PSF1, Peptide transporter TAP1
  9. Target

    Chromaffin granule amine transporter

    go.drugbank.com/bio_entities/BE0004674
    TargetHumans

    Transports catecholamines and indolamines with higher affinity for serotonin (PubMed:16326835, PubMed:23337945, PubMed:8643547). … Mediates presynaptic monoaminergic vesicle transport in the amygdala and prefrontal brain regions related with emotion processing in response to environmental stimuli (PubMed:23337945)

    Polypeptides: Chromaffin granule amine transporterSynonyms: Vesicular amine transporter 1
  10. Target

    Equilibrative nucleoside transporter 2

    go.drugbank.com/bio_entities/BE0004706
    TransporterTargetHumans

    Functions as a Na(+)-independent, passive transporter (PubMed:9478986). … Can also transport urate (PubMed:40367900). Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites (PubMed:12527552).

    Polypeptides: Equilibrative nucleoside transporter 2Synonyms: Nucleoside transporter, ei-type, Equilibrative NBMPR-insensitive nucleoside transporter