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Thrombin
go.drugbank.com/drugs/DB11300ApprovedInvestigationalAlso known as coagulation factor II, thrombin is a serine protease that plays a physiological role in regulating hemostasis and maintaining blood coagulation. … Medical thrombin is a protein substance produced through a conversion reaction in which prothrombin of bovine origin is activated by tissue thromboplastin in the presence of calcium chloride.
Mixtures: TISSEEL FIBRIN SEALANT VH S/D (FROZEN), TACHOSİL 5,5 MG/CM2 İNSAN FİBRİNOJENİ VE 2.0 IU/CM2 İNSAN TROMBİNİ İLAÇLI SÜNGERSynonyms: coagulation factor IILopinavir
go.drugbank.com/drugs/DB01601ApprovedInvestigationalLopinavir is an antiretroviral protease inhibitor used in combination with other antiretrovirals in the treatment of HIV-1 infection. … [L11163] Lopinavir is marketed and administered exclusively in combination with [ritonavir] - this combination, first marketed by Abbott under the brand name Kaletra in 2000, is necessary due to lopinavir's
Mixtures: LOPIMUNE ® + RITONAVIR 10 MG - PELLETS EN CÁPSULAS ORALES, LOPIMUNE®Categories: Antivirals used in combination for the treatment of HIV infections, Metabolic Side Effects of Drugs and SubstancesSulfaphenazole
go.drugbank.com/drugs/DB06729ApprovedSulfaphenazole is a sulfonamide antibacterial.
Categories: combinations of sulfonamides, Cytochrome P-450 CYP2B6 InhibitorsSynonyms: N'-(1-phenylpyrazol-5-yl)sulfanilamide, N(1)-(1-phenylpyrazol-5-yl)sulfanilamideHydroxypropyl cellulose
go.drugbank.com/drugs/DB00840ApprovedHydroxypropyl cellulose is an ether of cellulose where some of the hydroxyl groups of the cellulose have been hydroxypropylated forming -OCH2CH(OH)CH3 groups. … Lacrisertis a formulation of hydroxypropyl cellulose that is used for artificial tears.
Categories: Compounds used in a research, industrial, or household settingSynonyms: Cellulose, 2-hydroxypropyl ether, Hydroxypropyl cellulose (type H)Lithium carbonate
go.drugbank.com/drugs/DB14509ApprovedInvestigationalLithium has been used to treat manic episodes since the 19th century[A176642]. Though it is widely used, its mechanism of action is still unknown[FDA Label][A14585,A176642,A176651,L5843]. … Lithium carbonate has a narrow therapeutic range and so careful monitoring is required to avoid adverse effects[FDA Label].
Mixtures: BIOGROW MINCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Drugs that are Mainly Renally Excreted with a Narrow Therapeutic IndexRose bengal
go.drugbank.com/drugs/DB11182ApprovedInvestigationalRose bengal is a pink stain derived as an analogue of fluorescein. Its disodium salt in ophthalmic solutions has been used as a diagnostic agent in suspected damage to conjunctival and corneal cells. … It is also used in laboratory settings, including the preparation of Foraminifera for microscopic analysis and suppression of bacterial growth in several microbiological media.
Categories: Compounds used in a research, industrial, or household setting, Heterocyclic Compounds, 3-RingMalacidin B
go.drugbank.com/drugs/DB14052ExperimentalMalacidin B, along with [DB14051], is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria [A33312]. … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin B appears to act via its own distinct mechanism.
Synonyms: Malacidin BMalacidin A
go.drugbank.com/drugs/DB14051ExperimentalMalacidin A, along with [DB14052], is a member of a class of chemicals made by bacteria found in soil that can kill Gram-positive bacteria [A33312]. … While structurally similar to other macrocycle drugs like [DB00080] and [DB06087], Malacidin A appears to act via its own distinct mechanism.
Synonyms: Malacidin ADelamanid
go.drugbank.com/drugs/DB11637ApprovedInvestigationalMultidrug-resistant tuberculosis may also require more than 2 years of chemotherapy and second-line therapies with narrow therapeutic index [A31968]. … It is used in the treatment of multidrug-resistant and extensively drug-resistant tuberculosis (TB) in a combination regimen.
Categories: Drugs for Treatment of Tuberculosis, Cytochrome P-450 SubstratesSynonyms: (2R)-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)piperidin-1-yl)phenoxy)methyl)-2,3-dihydroimidazo(2,1-B)(1,3)oxazole, (R)-2-methyl-6-nitro-2-{4-[4-(4-trifluoromethoxyphenoxy)piperidin-1-yl]phenoxymethyl}-2,3-dihydroimidazo[2,1-b]oxazoleAloe vera leaf
go.drugbank.com/drugs/DB13906ApprovedInvestigationalWhile aloe vera has a long history of commercial uses, it is still widely used in cosmetic, food and pharmaceutical products. … Aloe describes a genus including over 500 species of flowering succulent plants that grow in the Southern peninsula and various islands.
Mixtures: Alcortin A, Alcortin AProducts: Secret No 1