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Fludeoxyglucose
go.drugbank.com/drugs/DB15107InvestigationalFludeoxyglucose is under investigation in clinical trial NCT03262389 (Comparison of F-18 FDG and C-11 Acetate PET in Multiple Myeloma).
Lovastatin
go.drugbank.com/drugs/DB00227ApprovedInvestigational[A181397, A181403] While all statin medications are considered equally effective from a clinical standpoint, [rosuvastatin] is considered the most potent; doses of 10 to 40mg [rosuvastatin] per day … Lovastatin, also known as the brand name product Mevacor, is a lipid-lowering drug and fungal metabolite derived synthetically from a fermentation product of _Aspergillus terreus_.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitorsSynonyms: (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate, 2β,6α-dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactoneBrinzolamide
go.drugbank.com/drugs/DB01194Approved[A2051] Brinzolamide was approved by the FDA in 1998 as a standalone product and in 2013 as a combination product with brimonidine tartrate. … [L35310,L35315] In Europe, it was also approved as a combination product with timolol in 2008.[L35320]
Mixtures: BRINZOLAMIDE E TIMOLOLO EG, BRINZOLAMIDE E TIMOLOLO EGCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesAtidarsagene autotemcel
go.drugbank.com/drugs/DB17538ApprovedInvestigationala lentiviral vector encoding the human arylsulfatase A (ARSA) gene. … [L45191] Libmeldy was granted orphan designation by the EMA in April 2007, and was issued a marketing authorization in the EU in December 2020 for the treatment of certain manifestations of metachromatic
Synonyms: Autologous CD34+ cell enriched population that contains haematopoietic stem and progenitor cells (HSPC) transduced ex vivo using a lentiviral vector encoding the human arylsulfatase A (ARSA) gene, Autologous CD34+ cells transduced with lentiviral vector which encodes for the aryl Sulfatase A complimentary deoxyribonucleic acid sequencePulmonary Embolism Acute Massive
go.drugbank.com/conditions/DBCOND0138765Synonyms: PE, PE - Pulmonary embolismSufentanil
go.drugbank.com/drugs/DB00708ApprovedInvestigationalSufentanil is an opioid analgesic that is used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. … This route of administration is intended to be a simple, effective, non-invasive analgesic option to enable healthcare professionals to rapidly manage acute pain without difficult intravenous or epidural
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 1-RingSynonyms: 舒芬太尼, N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamideDisopyramide Cardiac Action Pathway
smpdb.ca/view/SMP0126247Drug actionDisopyramide is a class 1A antiarrhythmic agent used to treat life-threatening ventricular arrhythmias. It can be found under the brand names Norpace and Rythmodan. A class I anti-arrhythmic agent (one that interferes directly with the d...
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Mexiletine Action Pathway (New)
smpdb.ca/view/SMP0126263Drug actionMexiletine is a class 1B antiarrhythmic agent used in the treatment of documented ventricular arrhythmias that warrant treatment. Mexiletine (INN) (sold under the brand names Mexitil and Namuscla) is a medication used to treat abnormal h...
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Procainamide Action Pathway (New)
smpdb.ca/view/SMP0126265Drug actionProcainamide is a class 1A antidysrythmIc as well as an anesthetic that is used to treat ventricular dysrhythmias, tachycardia and atrial fibrillation. Procainamide mainly inhibits sodium channels protein type 5 subunit alpha but also in...
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2Moricizine Action Pathway
smpdb.ca/view/SMP0126950Drug actionMoricizine is an antiarrhythmic used to treat arrhythmias (irregular heartbeats) and to maintain normal heart rate. it acts on heart muscles by inhibiting inward sodium channels. This results in a slowed atrioventricular nodal and His-Pu...
Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2